The control of insect pests and invasive weeds has become more species-selective because of activity-guided isolation, structure elucidation, and total synthesis of naturally produced substances with important biological activities. Examples of isolated compounds include insect pheromones, antifeedants, and prostaglandins, as well as growth regulators for plants and insects. Synthetic analogues of natural substances have been prepared to explore the relationships between chemical structure and observed biological activity. Recent scientific advances have resulted from better methods for the chemical synthesis of target compounds and better analytical methods. The capability of analytical instrumentation continues to advance rapidly, enabling new insights.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jf803828w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Influence of tannin-rich extract from commercial and gallocatechin on ovine cryopreserved semen viability.
Syst Biol Reprod Med
December 2025
Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa.
The objective of this study was to evaluate the effect of a tannin-rich extract from commercial (MTE_0), and gallocatechin, a flavonoid compound derived from , on the long-term viability and motility of cryopreserved ovine semen. Six fresh ejaculates obtained from six adult merino rams twice per week for three weeks were allocated to five aliquots (0, 12.5, 25, 50, and 100 µM gallocatechin added into the Optidyl™ extender) before cooling and cryopreservation.
View Article and Find Full Text PDFA Coarse-Grained Model Describing the Critical Micelle Concentration of Perfluoroalkyl Surfactants in Ionic Aqueous Phase.
Langmuir
March 2025
IFP Energies nouvelles, 1 et 4 Avenue de Bois Préau, 92852 Rueil-Malmaison, France.
In this study, dissipative particle dynamics (DPD) simulations were employed to determine the critical micelle concentration (CMC) of perfluoroalkyl and polyfluoroalkyl substances (PFAS) in ionic aqueous solutions. This approach provides precise CMC data for PFAS surfactants in the presence of various ionic species, thereby addressing a gap in the current literature. Additionally, this study contributes to the development of open-source molecular force fields for charged perfluorinated compounds, which are currently limited.
View Article and Find Full Text PDFRecent perspectives on biotechnological production, modulation and applications of glycerophosphoryl diester phosphodiesterases.
Biodegradation
March 2025
School of Biological Sciences, University of the Punjab, Lahore, Pakistan.
Organophosphate (OP) compounds have been extensively employed as pesticides, insecticides and nerve agents. Stockpiles of chemical warfare agents must be destroyed as recommended by Chemical Weapon Convention (CWC). Toxicity of OP compounds to insects and mammals is due to their ability to inhibit the activity of acetylcholinesterase.
View Article and Find Full Text PDFMultitarget Natural Compounds for Ischemic Stroke Treatment: Integration of Deep Learning Prediction and Experimental Validation.
J Chem Inf Model
March 2025
Department of Bioconvergence, Hoseo University, Asan 31499, South Korea.
Ischemic stroke's complex pathophysiology demands therapeutic approaches targeting multiple pathways simultaneously, yet current treatments remain limited. We developed an innovative drug discovery pipeline combining a deep learning approach with experimental validation to identify natural compounds with comprehensive neuroprotective properties. Our computational framework integrated SELFormer, a transformer-based deep learning model, and multiple deep learning algorithms to predict NC bioactivity against seven crucial stroke-related targets (, and ).
View Article and Find Full Text PDFComparative proteogenomics reveals ecological and evolutionary insights into the organohalide-respiring strain T.
Appl Environ Microbiol
March 2025
Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, Liaoning, China.
1,1,1-Trichloroethane (1,1,1-TCA) and chloroform (CF) are persistent groundwater contaminants because of their widespread industrial use as organic solvents and improper disposal in the past. Obligate organohalide-respiring bacteria (OHRB), such as (), play crucial roles in biotransforming and detoxifying natural or anthropogenic halogenated organics including 1,1,1-TCA and CF through reductive dechlorination. Despite their significance, only five strains have been associated with the reductive dechlorination of 1,1,1-TCA or CF.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!