Objective: To review the results of 78 revision stapedotomies, determining the causes of failure and the predictors of surgical success.
Study Design: Case series with chart review.
Setting: Tertiary referral center.
Subjects And Methods: Seventy-eight operations were performed in a tertiary referral center on 72 patients between 1995 and 2005. Indication for surgery was recurrent or persistent conductive hearing loss.
Results: The most common causes of failure were prosthesis displacement, incus necrosis, and oval window fibrosis. Postoperative air-bone gap was closed to within 10 dB in 54 percent of cases, and mean postoperative air-bone gap was 13.6 dB. Overclosure occurred in five percent of cases, sensorineural hearing loss in six percent of cases, and we had one postoperative dead ear. Success rates were higher in cases presenting prosthesis or ossicular malfunction than in cases with oval window problems. Hearing results did not differ if the prosthesis was crimped to either the malleus or the remnant of the long incudal process. Outcomes were similar for local or general anesthesia, and the nitinol piston did not significantly improve the hearing results.
Conclusion: Revision stapedotomy is less successful than primary procedure. Lessening the surgical trauma provides the most favorable results.
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http://dx.doi.org/10.1016/j.otohns.2009.03.028 | DOI Listing |
Transplant Proc
January 2025
Hepatobiliary Surgery and Liver Transplantation Unit, Cruces University Hospital, Bilbao, Spain; BioBizkaia Research Health Institute, Barakaldo, Bizkaia, Spain. Electronic address:
Polycystic liver disease (PLD) is a hereditary condition, and its symptoms are due to the growth of cysts. Liver transplantation (LT) is the only curative treatment. A retrospective single-center analysis was conducted on the 10 LTs performed for PLD between 2004 and 2023.
View Article and Find Full Text PDFClin Mol Hepatol
January 2025
Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Background/aims: Alcohol represents a leading burden of disease worldwide, including alcohol use disorder (AUD) and alcohol-related liver disease (ALD). We aim to assess the global burden of AUD, ALD, and alcohol-attributable primary liver cancer between 2000-2021.
Methods: We registered the global and regional trends of AUD, ALD, and alcohol-related liver cancer using data from the Global Burden of Disease 2021 Study, the largest and most up-to-date global epidemiology database.
Alzheimers Dement
December 2024
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Background: Fatigue is prevalent in later life and may increase dementia risk independent of health conditions. Yet, existing epidemiologic studies include samples that are not nationally representative of U.S.
View Article and Find Full Text PDFBackground: Evidence from diverse fields implicates lipid dysfunction in Alzheimer Disease (AD) pathogenesis. However, lipid consumption at the individual level does not vary greatly within most study cohorts, and multiple lipids are rarely well-measured concurrently. In contrast, mean lipid intakes at the country-level can be precisely estimated and can vary substantially across countries.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Newcastle University, Newcastle upon Tyne, United Kingdom.
Background: Dementia is a global public health concern, that poses daily challenges to the individuals, families, and healthcare systems worldwide. Sixty percent of those affected reside in low- and middle-income countries (LMICs), where 71% of new cases are anticipated by 2025. Most dementia studies focus on high-income countries, emphasizing the need for region-specific investigations in areas like Southeast Asia, where diverse cultural, economic, and healthcare settings present unique complexities.
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