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Tracing the Evolution of Prostate Brachytherapy in the 20th Century.
Oncology
March 2024
Department of Radiation Oncology, Centre Hospitalier de l'Université de Montréal, Montreal, Québec, Canada.
Background: Prostate brachytherapy (BT) techniques have evolved over the past century. This paper aimed to preserve our collective memory of history and the early development of its technique. We searched articles in PubMed and Google Scholar using keywords referring to authors, dates, and BT technical details, including different radioactive sources and country-specific publications.
View Article and Find Full Text PDFS-values for radium-223 and absorbed doses estimates for RACL using three computational phantoms.
Appl Radiat Isot
November 2022
Institute of Radiation Protection and Dosimetry, National Nuclear Energy Commission, Salvador Allende Ave., 3773, Recreio dos Bandeirantes, 22783-127, Rio de Janeiro, RJ, Brazil.
Radium-223 dichloride (RaCl2), approved by FDA (Food and Drug Administration) in 2013 and in Brazil by ANVISA (Agência Nacional de Vigilância Sanitária) in 2016, offers a new therapeutic option for bone metastases from castration-resistant prostate cancer (CRPC). The advantages of radionuclide therapy for bone metastases include the simultaneous treatment of multiple lesions at the same time. The activity prescription is based on the patient's body weight, disregarding the absorbed dose limit of 2 Gy in the organ at risk: bone marrow.
View Article and Find Full Text PDFEpidemiology of lung cancer.
Contemp Oncol (Pozn)
February 2021
Hematologist-Oncologist, Allegheny Health Network, Pittsburgh, PA, USA.
Lung cancer is the leading cause of global cancer incidence and mortality, accounting for an estimated 2 million diagnoses and 1.8 million deaths. Neoplasms of the lungs are the second most common cancer diagnosis in men and women (after prostate and breast cancer, respectively).
View Article and Find Full Text PDFDuring prostate cancer treatment with 223Ra. 219Rn (actinon) occurs and may be exhaled by the patient. Nurses and other hospital employees may inhale this radionuclide and its decay products.
View Article and Find Full Text PDFLung Cancer in Non-Smokers.
Mo Med
April 2021
Practice Pulmonary and Critical Care medicine in the Truman Medical Center Health Sciences District, Kansas City, Missouri.
Lung cancer is the leading cause of cancer death worldwide and the third most common cancer following breast and prostate.1 As expected, the primary factor leading to lung cancer is tobacco smoke, and as smoking rates have declined, we have also seen an overall decline in lung cancer rates.2 Despite the general reduction in lung cancer rates, the rate of lung cancer in non-smokers has been noted to be increasing.
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