Unlabelled: Enteric viruses are important causative agents of human diseases. Among the enteric viruses, reoviruses and enteroviruses are prevalent in various aquatic environments. This study was carried out to detect and compare the presence of reoviruses and enteroviruses by ICC-PCR in one wastewater and three drinking water treatment plants, studying the possibility of using reoviruses as indicator of viral water pollution and genotyping of the isolated strains. One hundred and forty four drinking water and 76 wastewater samples were collected for two years. Reoviruses and enteroviruses were detected in 12.5% (18/144) and 8.3% (12/144) of total collected drinking water samples. In the studied wastewater treatment plant (WWTP), reoviruses were detected in 26% (20/76) of total collected samples while enteroviruses were detected in 21% (16/76) of the total collected samples. Phylogenic analysis revealed that our sequences were closely related to reovirus type 1, Lang strain and Human poliovirus type1.
Conclusion: The higher incidence of reoviruses than enteroviruses reflects the possibility of using reoviruses as indicator of water pollution.
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Int J Biol Macromol
August 2024
Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China. Electronic address:
Clin Exp Med
November 2023
Department of Clinical Immunology Allergy and AIDS, Kaplan Medical Center, Rehovot, Israel.
The aim of this review is to provide a comprehensive overview about the link between viruses and celiac disease. A systematic search on PubMed, Embase, and Scopus was conducted on March 07, 2023. The reviewers independently selected the articles and chose which articles to include.
View Article and Find Full Text PDFEnviron Sci Technol
August 2020
Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.
Free-living amoebae (FLA) are ubiquitous protozoa in aquatic/soil habitats and known to resist various disinfection methods commonly used in drinking and wastewater treatment plants. Reoviruses are emerging as useful infectious enteric virus indicators of wastewater treatment efficacy. The possible enhanced protection FLA may provide reoviruses, however, has not been previously described.
View Article and Find Full Text PDFExpert Opin Biol Ther
June 2020
Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK.
: Immune checkpoint inhibitors (ICI) have dramatically improved the outcome for cancer patients across multiple tumor types. However the response rates to ICI monotherapy remain relatively low, in part due to some tumors cultivating an inherently 'cold' immune microenvironment. Oncolytic viruses (OV) have the capability to promote a 'hotter' immune microenvironment which can improve the efficacy of ICI.
View Article and Find Full Text PDFOncolytic Virother
July 2019
SATOR Therapeutics LLC , Cleveland, OH 44106, USA.
Viruses have some characteristics in common with cell-based life. They can evolve and adapt to environmental conditions. Directed evolution can be used by researchers to produce viral strains with desirable phenotypes.
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