We used 909 strains to compare the population structures of the Mycobacterium tuberculosis Beijing family between different birth-year cohorts in Japan. The results revealed that the spread of a modern sublineage that has high transmissibility is currently increasing, while the spread of an ancient sublineage, STK, has significantly decreased in younger generations.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756919PMC
http://dx.doi.org/10.1128/JCM.01061-09DOI Listing

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