An analytical treatment of the nonlinear kinetic equations for fast relaxation of coexisting short and lengthy micelles in surfactant solutions is presented. The kinetic equations can be written as a hierarchical set of differential equations for the moments of the aggregation number distribution function of micelles. It is shown that the moment equations can be successively integrated. As examples of the general approach, particular cases of short spherical micelles, lengthy cylindrical micelles, and coexisting short and lengthy micelles have been considered and compared to the results of linear kinetic theory of micellar fast relaxation. The results show that there is a strong interplay between coexisting short and lengthy micelles, even in the case when the total number of surfactant molecules aggregated in short micelles is small in comparison with that in lengthy micelles.
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http://dx.doi.org/10.1063/1.3204699 | DOI Listing |
ACS Nano
October 2020
Huygens-Kamerlingh Onnes Laboratory, Leiden University, Postbus 9504, 2300 RA Leiden, The Netherlands.
Optical detection of individual nanometer-sized analytes, virus particles, and protein molecules holds great promise for understanding and control of biological samples and healthcare applications. As fluorescent labels impose restrictions on detection bandwidth and require lengthy and invasive processes, label-free optical techniques are highly desirable. Here, we introduce an optical technique capable of transforming gold nanorods commonly used as photostable labels into highly localized high-speed probes.
View Article and Find Full Text PDFJ Chromatogr A
October 2015
Departament de Química Analítica and Institut de Biomedicina (IBUB), Universitat de Barcelona, Martí i Franquès 1-11, 08028 Barcelona, Spain.
Toxicity has been emulated in tadpole species through chromatographic systems. The parameter studied to evaluate the non-specific toxicity of a compound is the narcosis concentration (Cnar), which is defined as the concentration needed for the immobilization of the organism. Because experimental investigation with animals is lengthy, costly, technically difficult, and ethically questionable, there is a great interest in developing surrogate physicochemical systems able to emulate biological systems to obtain the same information in a faster, more economic, and easier manner.
View Article and Find Full Text PDFJ Phys Chem B
May 2014
Departamento de Física de la Materia Condensada, Grupo de Física de Coloides y Polímeros , 15782-Santiago de Compostela, Spain.
Amphiphilic block copolymers have emerged during last years as a fascinating substrate material to develop micellar nanocontainers able to solubilize, protect, transport, and release under external or internal stimuli different classes of cargos to diseased cells or tissues. However, this class of materials can also induce biologically relevant actions, which complement the therapeutic activity of their cargo molecules through their mutual interactions with biologically relevant entities (cellular membranes, proteins, organelles..
View Article and Find Full Text PDFJ Chem Phys
August 2009
Department of Statistical Physics, St. Petersburg State University, Ulyanovskaya St. 1, Petrodvorets, St. Petersburg 198504, Russia.
An analytical treatment of the nonlinear kinetic equations for fast relaxation of coexisting short and lengthy micelles in surfactant solutions is presented. The kinetic equations can be written as a hierarchical set of differential equations for the moments of the aggregation number distribution function of micelles. It is shown that the moment equations can be successively integrated.
View Article and Find Full Text PDFInt J Pharm
March 2009
Department of Organic and Inorganic Chemistry, Polymer Laboratory, Federal University of Ceará, CX 12.200, CEP 60455-760, Fortaleza, Ceará, Brazil.
The influence of hydrophobic-block length on solubilisation capacity was examined for micelles of E(m)B(n) copolymers (E=oxyethylene, B=oxybutylene, subscripts denote number-average block lengths in repeat units) with B-block lengths in the range of 30-76 and with E-blocks of sufficient length to ensure the formation of spherical micelles. Griseofulvin was used as a model poorly-water-soluble drug known to be almost exclusively solubilised in the micellar core. Combination of solubilisation data with those of a previous study has shown that the amount of drug solubilised per gram of hydrophobe is essentially independent of B-block length when this exceeds about 15 B units, suggesting that core size is not a major influence on solubilisation.
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