Obesity, particularly severe obesity, affects resting and exercise-related respiratory physiology. Severe obesity classically produces a restrictive ventilatory abnormality characterized by reduced expiratory reserve volume. Obstructive ventilatory abnormality may also be associated with abdominal obesity. Decreased peak work rates are usually seen among obese subjects in a setting of normal or decreased ventilatory reserve and normal cardiovascular response to exercise. Weight loss may reverse many adverse physiologic consequences of severe obesity on the respiratory system.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765111 | PMC |
| http://dx.doi.org/10.1016/j.ccm.2009.05.003 | DOI Listing |
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