We assessed hemisphere function in right-handed male chronic schizophrenic patients using dichotic listening tests. We evaluated digit, tonic and transitional tests in patients with paranoid schizophrenia (n = 8), patients with disorganized schizophrenia (n = 8) and in control subjects (n = 8). The dichotic listening analysis discriminated between paranoid and disorganized schizophrenia. In disorganized schizophrenia, functional impairment of both hemispheres was demonstrated, while in paranoid schizophrenia dysfunction was more prominent in the right hemisphere. These results indicate the possible involvement of right hemisphere dysfunction in the pathophysiology of chronic paranoid schizophrenia, in contrast to dysfunction of both hemispheres in chronic disorganized schizophrenia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0924-9338(96)88387-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Low Versus High Levels of Social Cognition Impairment and Their Associations With Specific Schizophrenia Symptom Domains.
J Neuropsychiatry Clin Neurosci
January 2025
Department of Psychology, Chung Shan Medical University, and Clinical Psychological Room, Chung Shan Medical University Hospital, Taichung, Taiwan (Huang); Department of Psychology, Fo Guang University, Yilan, Taiwan (Chen); Come a New Halfway House, Taoyuan, Taiwan (Wang); Department of Psychiatry, National Cheng Kung University Hospital (Kuo, Yang, Tseng), and Institute of Behavioral Medicine (Yang, Tseng), College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Objective: Social cognition is defined as the ability to construct mental representations about oneself, others, and one's relationships with others to guide social behaviors, including referring to mental states (cognitive factor) and understanding emotional states (affective factor). Difficulties in social cognition may be symptoms of schizophrenia. The authors examined associations between two factors of social cognition and specific schizophrenia symptoms, as well as a potential path from low-level affective perceptual social cognition to high-level social cognition, which may be associated with schizophrenia symptoms.
View Article and Find Full Text PDFSchizotypal dimensions by migrant status in the general population: An exploratory study.
Schizophr Res
January 2025
AP-HP, Hôpitaux Universitaires "H. Mondor", DMU IMPACT, INSERM, IMRB, translational Neuropsychiatry, Fondation FondaMental, Univ Paris-Est-Créteil (UPEC), Créteil, France.
Article Synopsis
- Research shows that migrant status and ethnic minority background increase the risk of psychosis, but it's unclear if this also applies to subclinical psychosis.
- In a study with 460 participants, first and second-generation migrants, as well as certain ethnic minorities, reported higher levels of negative psychotic traits compared to a reference population.
- These findings suggest a connection between negative schizotypal traits and migrant/ethnic status, indicating a need for specific mental health interventions to support these groups and prevent the development of psychotic disorders.
Facial Emotion Recognition and its Associations With Psychological Well-Being Across Four Schizotypal Dimensions: a Cross-Sectional Study.
Arch Clin Neuropsychol
January 2025
Laboratory of Neuropsychology, Department of Psychology, School of Social Sciences, Gallos University campus, University of Crete, Rethymno 74100, Greece.
Objective: The present study aimed to examine facial emotion recognition in a sample from the general population with elevated schizotypal traits, as defined by the four-factor model of schizotypy, and the association of facial emotion recognition and the schizotypal dimensions with psychological well-being.
Method: Two hundred and thirty-eight participants were allocated into four schizotypal groups and one control group. Following a cross-sectional study design, facial emotion recognition was assessed with a computerized task that included images from the Radboud Faces Database, schizotypal traits were measured with the Schizotypal Personality Questionnaire, and psychological well-being was evaluated with the Flourishing scale.
Disentangling the topological symptom structure of schizophrenia: A network analysis.
Schizophr Res
December 2024
Department of Psychiatry, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan International Joint Laboratory of Biological Psychiatry, Zhengzhou University, Zhengzhou, China; Henan Psychiatric Transformation Research Key Laboratory, Zhengzhou University, Zhengzhou, China. Electronic address:
Background And Hypothesis: The Positive and Negative Syndrome Scale (PANSS), comprehensively assesses schizophrenia severity. While network analyses of schizophrenic symptoms have yielded inconsistent results, components of disorganized thought consistently rank high in centrality. The present study aims to explore the centrality of disorganized thought across patient subgroups and its potential as a treatment target.
View Article and Find Full Text PDFBrain-clinical pattern alterations after treatment in schizophrenia.
Cereb Cortex
November 2024
Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Chinese Academy of Medical Sciences Research Unit (No.2018RU006), Peking University, 51 Huayuanbei Road, Haidian District, Beijing 100191, China.
Discovering meaningful brain-clinical patterns would be a significant advancement for elucidating the pathophysiology underlying schizophrenia. In the present study, we analyzed associations between functional brain characters (average functional connectivity strength and its fluctuations) and clinical features (age onset, illness duration, and positive, negative, disorganized, excited, and depressed) using partial least squares. Also, we analyzed the brain-clinical relationship changes after 6-wk of treatment.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!