Aim: Patients with schizophrenia frequently report disturbed sleep and excessive daytime sleepiness. In this study the sleep quality and daytime sleepiness of patients hospitalized due to psychotic disorders was assessed shortly before the discharge from the hospital.
Method: 62 patients treated with antipsychotics (20 F/ 42 M, mean age 25.7 +/- 3.5) were examined. The patients performed a vigilance task (Mackworth clock test), clinical scales were used for the assessment of: sleep quality (Athens insomnia scale - AIS), daytime sleepiness (Epworth sleepiness scale - ESS), clinical global impression (CGI scale), drug side effects (UKU scale), psychopathology and depressive symptoms (PANSS and CDSS scales).
Results: Excessive daytime sleepiness (EDS) was reported in the UKU scale in 58% of the patients. This subjective sensation of EDS was not reflected in the results of the standardized methods for the assessment of EDS. In the ESS scale EDS was found in 20% of the patients. A disturbed vigilance was found in the vigilance task in 32% of the patients.
Conclusion: Subjective feeling of EDS is common in patients treated with antipsychotics. The ESS scale allows to verify the patients' claims. EDS resulting from disturbed or shortened sleep, should be differentiated from sedation resulting from pharmacological treatment and fatigue that may be related to somatic or mental disorders.
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Eur J Pediatr
January 2025
Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Unlabelled: Klinefelter syndrome (KS) is the most common sex chromosomal aneuploidy in males (47,XXY karyotype in 80-90% of cases), primarily characterized by hypergonadotropic hypogonadism and infertility. It encompasses a broad phenotypic spectrum, leading to variability in neurocognitive and psychosocial outcomes among affected individuals. Despite the recognized correlation between KS and various neuropsychiatric conditions, studies investigating potential sleep disorders, particularly in pediatric subjects, are lacking.
View Article and Find Full Text PDFJ Clin Sleep Med
January 2025
Fundación Neumológica Colombiana, Bogotá, Colombia.
Study Objectives: REM-associated OSA (REM OSA) has a prevalence of 17-74% of all OSA cases. At high altitude and in Latin America, there are no data on REM OSA and its relationship to daytime sleepiness and comorbidities. This study aimed to determine the prevalence of REM OSA and the differences in clinical and polysomnographic characteristics between OSA and REM OSA in a population living at 2640 m.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia.
Sleep is the most important physiological function of all animals studied to date. Sleep disorders include narcolepsy, which is characterized by excessive daytime sleepiness, disruption of night sleep, and muscle weakness-cataplexy. Narcolepsy is known to be caused by the degeneration of orexin-synthesizing neurons (hypocretin (HCRT) neurons or orexin neurons) in the hypothalamus.
View Article and Find Full Text PDFRes Dev Disabil
January 2025
Dalian Medical University, Dalian, Liaoning, China; Department of Child Health, Dalian Municipal Women and Children's Medical Center (Group), Dalian, Liaoning, China. Electronic address:
Introduction: Recent studies have shown a close relationship between attention-deficit hyperactivity disorder (ADHD) and allergic diseases in children. Regrettably, few studies have investigated the effect of comorbid allergies on ADHD symptoms and sleep, in particular, it is unclear whether comorbid allergic conditions further exacerbate sleep problems in children with ADHD.
Objective: To investigate the effect of comorbid allergic on symptoms and sleep in children with ADHD.
Medicine (Baltimore)
January 2025
Pediatrics Department, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, Gansu, China.
This retrospective study aims to assess the adjunctive efficacy of warm needle moxibustion and gua sha care in the treatment of eszopiclone tablets on sleep quality and psychological stress in insomnia patients. Data of 138 insomnia patients from Gansu Baoshihua hospital between January and December 2022 were collected. Patients were bifurcated into 2 groups: those solely treated with eszopiclone (n = 71) and those administered a combined regimen of eszopiclone, warm needle moxibustion, and gua sha (n = 67).
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