In this paper, we present a probabilistic neural model, which extends Kohonen's self-organizing map (SOM) by performing a probabilistic principal component analysis (PPCA) at each neuron. Several SOMs have been proposed in the literature to capture the local principal subspaces, but our approach offers a probabilistic model while it has a low complexity on the dimensionality of the input space. This allows to process very high-dimensional data to obtain reliable estimations of the probability densities which are based on the PPCA framework. Experimental results are presented, which show the map formation capabilities of the proposal with high-dimensional data, and its potential in image and video compression applications.
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http://dx.doi.org/10.1109/TNN.2009.2025888 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Guangdong Institute of Intelligence Science and Technology, 519031 Hengqin, Zhuhai, Guangdong, China.
Manifold learning techniques have emerged as crucial tools for uncovering latent patterns in high-dimensional single-cell data. However, most existing dimensionality reduction methods primarily rely on 2D visualization, which can distort true data relationships and fail to extract reliable biological information. Here, we present DTNE (diffusive topology neighbor embedding), a dimensionality reduction framework that faithfully approximates manifold distance to enhance cellular relationships and dynamics.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Economics, Columbia University, New York, NY 10027.
Measuring and interpreting errors in behavioral tasks is critical for understanding cognition. Conventional wisdom assumes that encoding/decoding errors for continuous variables in behavioral tasks should naturally have Gaussian distributions, so that deviations from normality in the empirical data indicate the presence of more complex sources of noise. This line of reasoning has been central for prior research on working memory.
View Article and Find Full Text PDFStat Med
February 2025
Department of Mathematical Sciences, The University of Texas at Dallas, Richardson, Texas.
Advances in next-generation sequencing technology have enabled the high-throughput profiling of metagenomes and accelerated microbiome studies. Recently, there has been a rise in quantitative studies that aim to decipher the microbiome co-occurrence network and its underlying community structure based on metagenomic sequence data. Uncovering the complex microbiome community structure is essential to understanding the role of the microbiome in disease progression and susceptibility.
View Article and Find Full Text PDFTomography
January 2025
Department of Radiology, University of Padova, 35127 Padova, Italy.
This commentary examines Topological Data Analysis (TDA) in radiology imaging, highlighting its revolutionary potential in medical image interpretation. TDA, which is grounded in mathematical topology, provides novel insights into complex, high-dimensional radiological data through persistent homology and topological features. We explore TDA's applications across medical imaging domains, including tumor characterization, cardiovascular imaging, and COVID-19 detection, where it demonstrates 15-20% improvements over traditional methods.
View Article and Find Full Text PDFJ Intell
January 2025
School of Social Sciences, Tsinghua University, Beijing 100084, China.
As psychological research progresses, the issue of concept overlap becomes increasing evident, adding to participant burden and complicating data interpretation. This study introduces an Embedding-based Semantic Analysis Approach (ESAA) for detecting redundancy in psychological concepts, which are operationalized through their respective scales, using natural language processing techniques. The ESAA utilizes OpenAI's text-embedding-3-large model to generate high-dimensional semantic vectors (i.
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