Ethyl 6-O-acetyl-2,3,4-tribenzyl-1-thio-d-glucopyranoside, as a mixture of anomers, was employed for the stereoselective synthesis of the potassium salt of (2R)-2-O-alpha-d-glucopyranosyl-(1-->6)-alpha-d-glucopyranosyl-2,3-dihydroxypropanoic acid (alpha-d-glucosyl-(1-->6)-alpha-d-glucosyl-(1-->2)-d-glyceric acid, GGG), a recently isolated compatible solute. The alpha-anomer was by far the major product of both glycosylation reactions using NIS/TfOH as activator.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.carres.2009.06.037 | DOI Listing |
Publication Analysis
Top Keywords
synthesis potassium
8
compatible solute
8
potassium 2r-2-o-alpha-d-glucopyranosyl-1-->6-alpha-d-glucopyranosyl-23-dihydroxypropanoate
4
2r-2-o-alpha-d-glucopyranosyl-1-->6-alpha-d-glucopyranosyl-23-dihydroxypropanoate natural
4
natural compatible
4
solute ethyl
4
ethyl 6-o-acetyl-234-tribenzyl-1-thio-d-glucopyranoside
4
6-o-acetyl-234-tribenzyl-1-thio-d-glucopyranoside mixture
4
mixture anomers
4
anomers employed
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!