CO(2) laser therapy in Tis and T1 glottic cancer: indications and results.

Head Neck

Department of Oto-Neuro-Ophthalmological Surgical Sciences, Division of Otorhinolaryngology-Head and Neck Surgery, University of Florence, Florence, Italy.

Published: March 2010

Background: Laser cordectomy for glottic cancer is still hampered by recurrence, which is more frequent upon anterior commissure (AC) involvement. Analysis of results may be a step to improve the efficacy of this therapy for early glottic cancer.

Methods: In all, 81 patients who underwent surgery with CO(2) laser for Tis and T1, AC0 to AC2 glottic carcinoma were followed up to 55 months.

Results: The incidence of recurrence increased significantly with T and AC classifications. The disease-free interval decreased with increasing T and AC classifications and with increasing severity of histology, but only the AC classification appeared significant. Recurrences occurred in 5 of 35 patients upon type I and type II cordectomy, in 16 of 24 patients upon type V cordectomy, and never upon type III and IV cordectomy.

Conclusions: Type I to type IV cordectomy, when indicated, can achieve radical treatment of most T1 glottic cancer. Type V cordectomy requires that any suspicion of cartilage invasion, even microscopic, be excluded.

Download full-text PDF

Source
http://dx.doi.org/10.1002/hed.21200DOI Listing

Publication Analysis

Top Keywords

type cordectomy
16
glottic cancer
12
co2 laser
8
patients type
8
type type
8
type
7
glottic
5
cordectomy
5
laser therapy
4
therapy tis
4

Similar Publications

The recommended treatment for early glottic cancer is trans-oral laser microsurgery, with excellent oncological and functional outcomes. The aim of this study is to evaluate oncological and functional outcomes in patients who underwent monolateral type III laser cordectomy for early glottic cancer. A total of 104 patients were enrolled.

View Article and Find Full Text PDF

Voice Quality After Anterior Commissure Cordectomy Versus Marginal Cordectomy for cT1 Glottic Carcinoma: A Case-Series.

Otolaryngol Head Neck Surg

December 2024

Research Committee, Young Otolaryngologists of the International Federation of Otorhinolaryngological Societies (IFOS), Paris, France.

Objectives: To compare the presurgical to postsurgical voice quality (VQ) outcomes of types I, II, III, and VI transoral laser cordectomies (TLC).

Study Design: Prospective uncontrolled study.

Setting: Multicenter study.

View Article and Find Full Text PDF

[Analysis of long-term efficacy of CO laser partial excision of vocal folds for 599 cases in the treatment of vocal cord leukoplakia].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

October 2024

Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University; Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University), Ministry of Education, Beijing 100730, China.

To analyze long-term prognosis and influencing factors of recurrence in vocal fold leukoplakia treated by endoscopic cordectomy with CO laser. A retrospective review was conducted on 599 patients with vocal fold leukoplakia [566 males and 33 females, aged 17-84 years (median age 55 years)], undergoing endoscopic cordectomy by CO laser under general anesthesia at the Department of Otorhinolaryngology Head and Neck Surgery of Beijing Tongren Hospital, Capital Medical University, from January 2000 to December 2023. The study analyzed the clinical features, pathological grade, surgical methods, postoperative voice function, recurrence, malignant changes and analyzed the long-term efficacy and and its influencing factors.

View Article and Find Full Text PDF
Article Synopsis
  • * It involved 35 patients with bilateral vocal cord cancer, split into a study group (ADM membrane treatment) and a control group (silicone tube stent only).
  • * Results showed that the ADM group had fewer instances of granulation tissue and postoperative complications like tissue adhesion and laryngeal obstruction compared to the control group.
View Article and Find Full Text PDF

Too Deep: The Rate of Inappropriate Deep Resections while Practicing a Single Stage Laser Cordectomy.

J Voice

May 2024

Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: Whenever a cortectomy is indicated, obviating preoperative biopsy and practicing a single-stage-laser-cordectomy (SSLC) may expedite treatment and preserve surgical planes. This may result in more superficial resections and improved vocal function. Yet, SSLC holds a risk for over-treating nonmalignant lesions.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!