The use of nickel in certain consumer goods has been regulated in Denmark since 1990. The aim of this study was to reveal the clinical characteristics of nickel-allergic patients seen in seven private dermatology clinics and to identify current sources of nickel that may elicit nickel dermatitis. During 2006 to 2007, 634 patients with dermatitis aged 17-91 years were patch-tested and completed a questionnaire including a question about the occurrence of dermatitis following skin contact with ear-rings or ear-pins, watches, buttons or metal clasps (i.e. metal dermatitis). chi2 tests were applied to test for statistical significant differences. Analysis revealed a lower prevalence of nickel allergy among women in the youngest age group (17-22 years) in comparison with older age groups (23-34 years and 35-46 years) (p < 0.03). Most patients experienced metal dermatitis on the first occurrence be-tween 1975 and 1985. No new cases of metal dermatitis were identified after 1985. We conclude that nickel allergy has decreased among young females with dermatitis due to the nickel regulation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2340/00015555-0649 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Allergens Responsible for Contact Allergy in Children From 2010 to 2024: A Systematic Review and Meta-Analysis.
Contact Dermatitis
January 2025
Department of Dermatology and Allergy, Herlev and Gentofte-Copenhagen University Hospital, Copenhagen, Denmark.
Contact allergy (CA) is a frequent condition in children; however, newer estimates of the prevalence of CA in children are lacking. Herein, we aim to provide an estimate of the prevalence of CA in children from 2010 to 2024. Two authors independently searched PubMed, Embase and Web of Science for studies reporting the prevalence of positive patch tests (PPTs) to allergens in populations including ≥ 100 children (< 18 years).
View Article and Find Full Text PDFDesign and synthesis of a carbohydrate-derived chemosensor for selective Ni(II) ion detection: A turn-off approach.
Carbohydr Res
March 2025
Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007, India; Department of Chemistry, Ramjas College, University of Delhi, Delhi, 110007, India. Electronic address:
Nickel, an essential transition metal, plays a vital role in biological systems and industries. However, exposure to nickel can cause severe health issues, such as asthma, dermatitis, pneumonitis, neurological disorders, and cancers of the nasal cavity and lungs. Due to nickel's toxicity and extensive industrial use, efficient sensors for detecting Ni ions in environmental and biological contexts are essential.
View Article and Find Full Text PDFThe association between skin allergy testing and oral squamous cell carcinoma in oral lichen planus: a retrospective cohort study.
Arch Dermatol Res
January 2025
Department of Dermatology, Autoimmune Skin Diseases Clinic, University of Utah Spencer F. Eccles School of Medicine, 30 N Mario Capecchi Drive level 1 South, Salt Lake City, 84132, UT, USA.
There is a reported association between oral contact allergy and oral lichen planus (OLP). Likewise oral squamous cell carcinoma (oSCC) is associated with OLP. It is hypothesized that chronic inflammation may contribute to oSCC risk.
View Article and Find Full Text PDFNickel-induced labial angioedema in a pediatric patient with orthodontic braces: a case report.
Ital J Pediatr
January 2025
Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, 00161, Italy.
Background: Angioedema is a condition marked by sudden, intense swelling of the subcutaneous and submucosal tissues, typically associated with hypersensitivity reactions, genetic mutations, or reactions to medications. It can also result from contact with allergens such as nickel, leading to dermatitis.
Case Presentation: A 12-year-old girl presented at our Pediatric Immunology and Allergology service with recurrent labial angioedema for over a year, linked to the consumption of legumes and tomatoes, and following the use of a metal flute.
δ-Toxin Induces Ca Influx-Independent Degranulation of Murine Cultured Mast Cells.
Biol Pharm Bull
December 2024
Laboratory of Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University.
Cutaneous colonization with Staphylococcus aureus (SA) is frequently observed in patients with atopic dermatitis. SA produces a wide variety of bacterial toxins, among which δ-toxin was found to induce degranulation of mast cells. Degranulation of mast cells could enhance bacterial clearance and protection from future SA infection but lead to exacerbation of atopic dermatitis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!