Background: Disregard for rules, an important dimension of oppositional defiant and conduct disorders, is frequent during early childhood, but the development of its chronic form has not been studied during this key socialization period. This study aimed to describe the developmental trajectories of disregard for rules during early childhood and identify prenatal and postnatal predictors for a high trajectory.
Methods: Participants were involved in a longitudinal study of a birth cohort followed yearly from 5 to 74 months of age (N = 1,942). Prenatal and postnatal predictors were measured by parental report at the beginning of the study, and parents reported child disregard for rules at five time points from 29 to 74 months of age.
Results: Four groups of children followed distinct and stable trajectories of mother-rated disregard for rules: Very Low (approximately 9.1%), Low (56.9%), Moderate (29.7%) and Chronic (4.3%). As expected, male sex was a significant predictor of the chronic trajectory (OR = 1.76, CI = 1.09-2.83). Mothers' history of antisocial behavior (OR = 1.72, CI = 1.02-2.91), and postnatal depressive symptoms experienced by the mother (OR = 1.71, CI = 1.03-2.84) and the father (OR = 2.02, CI = 1.10-3.71) were also important independent predictors. However, contrary to expectations, children's difficult temperament and parenting at 5 months did not predict chronic disregard for rules beyond other risk factors.
Conclusions: High disregard for rules is fairly stable during early childhood and is associated with risk factors identifiable before and shortly after birth which may be used for targeted prevention.
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http://dx.doi.org/10.1111/j.1469-7610.2009.02118.x | DOI Listing |
Dev Psychopathol
November 2024
Department of Psychological and Brain Sciences, The University of Iowa, Iowa City, US.
The importance of interactions between child temperament and parenting has been accepted ever since Thomas and Chess (1977) proposed their "goodness-of-fit" construct, but over the last three decades, pertinent research has grown exponentially. Researchers examining child characteristics that can moderate the effects of socialization have tested increasingly complex, nuanced, and sophisticated models, largely inspired by the highly influential frameworks of child plasticity or differential susceptibility (Belsky & Pluess, 2009). Yet, multiple questions remain unsettled.
View Article and Find Full Text PDFBrief Bioinform
September 2024
Department of Informatics, University of Oslo, Gaustadalléen 23B, 0373 Oslo, Norway.
Adaptive immune receptors, such as antibodies and T-cell receptors, recognize foreign threats with exquisite specificity. A major challenge in adaptive immunology is discovering the rules governing immune receptor-antigen binding in order to predict the antigen binding status of previously unseen immune receptors. Many studies assume that the antigen binding status of an immune receptor may be determined by the presence of a short motif in the complementarity determining region 3 (CDR3), disregarding other amino acids.
View Article and Find Full Text PDFInt J Adolesc Med Health
October 2024
Department of Social and Behavioral Health, School of Public Health, University of Nevada, Las Vegas (UNLV), Las Vegas, NV, USA.
Background: Motorcyclists constitute the highest proportion of victims of road traffic accidents. Riding a motorcycle without a license in teenagers is one of the accident-causing behaviors. Therefore, the current study was conducted with the aim of qualitatively investigating the obstacles and underlying factors of utilizing a motorcycle without a license among adolescent boys in Iran.
View Article and Find Full Text PDFAn Acad Bras Cienc
September 2024
Universidade Federal do Piauí, Departamento de Biofísica e Fisiologia, Laboratório de Cancerologia Experimental (LabCancer), Campus Universitário Ministro Petrônio Portella, Ininga, 64049-550 Teresina, PI, Brazil.
Several countries and non-governmental organizations have discussed the use of animals in industry and biomedical areas. This work shows the progression of animal' rights for scientific purposes in Brazil and how Brazilian Councils have advanced to follow worldwide regulations. Since the first rules about animals' usage in Ireland in 1635, the British Cruelty to Animals Act in 1876, and the Brazilian animal protection rules in 1924 and 1934, most worldwide actions culminated in the Universal Declaration of Animal Rights (1978).
View Article and Find Full Text PDFBMC Med Ethics
September 2024
Faculty of Medicine, Institute of Health and Society, Centre for Medical Ethics, University of Oslo, Gaustadalléen 21, Oslo, 0349, Norway.
Background: The growing number of older people worldwide poses challenges for health policy, particularly in the Global North, where policymakers increasingly expect seniors to live and receive care at home. However, healthcare professionals, particularly in home-based care, face dilemmas between adhering to care ideals and meeting external demands. Although they strive to uphold ethical care standards, they must deal with patients' needs, cooperation with colleagues and management guidelines.
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