We demonstrate a four-stage optical parametric chirped-pulse amplification system that delivers carrier-envelope phase-stable approximately 1.5 microm pulses with energies up to 12.5 mJ before recompression. The system is based on a fusion of femtosecond diode-pumped solid-state Yb technology and a picosecond 100 mJ Nd:YAG pump laser. Pulses with 62 nm bandwidth are recompressed to a 74.4 fs duration close to the transform limit. To show the way toward a terawatt-peak-power single-cycle IR source, we demonstrate self-compression of 2.2 mJ pulses down to 19.8 fs duration in a single filament in argon with a 1.5 mJ output energy and 66% energy throughput.
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http://dx.doi.org/10.1364/ol.34.002498 | DOI Listing |
Physiol Res
November 2017
Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
In ischemic/reperfusion (I/R) injured hearts, severe oxidative stress occurs and is associated with intracellular calcium (Ca(2+)) overload. Glucagon-Like Peptide-1 (GLP-1) analogues have been shown to exert cardioprotection in I/R heart. However, there is little information regarding the effects of GLP-1 analogue on the intracellular Ca(2+) regulation in the presence of oxidative stress.
View Article and Find Full Text PDFPhysiol Res
March 2017
Second Department of Internal Medicine, Faculty Hospital Královské Vinohrady, Prague, Czech Republic. or
The study investigates the relationship between the labile iron pool (LIP) in circulating monocytes and markers of iron metabolism, inflammation, oxidative stress, endothelial dysfunction and arterial elasticity in patients with chronic cardiovascular disease and in healthy volunteers. The patients with a history of CVEs had significantly higher LIP values than did the control group (1.94+/-0.
View Article and Find Full Text PDFPhysiol Res
May 2016
Laboratoire de Recherche en Physiologie et Physiopathologie, Pôle Technologie Santé, Faculté de Médecine, Université Saint Joseph, Beyrouth, Liban.
Atrial natriuretic peptide antifibrotic properties are mainly described in cardiac myocytes or in induced cardiac myofibroblasts (Angiotensin II or TGF-beta induced differentiation). In the present work, we investigate the effects of ANP/NPRA/cGMP system in modulating rat cardiac fibroblasts function. Cardiac fibroblasts were isolated from adult Wistar male rats and cultured in the presence of serum in order to induce fibroblasts differentiation.
View Article and Find Full Text PDFThe cardiovascular pleiotropic effects of statins and a Rho-kinase inhibitor (fasudil) could be of interest to prevent myocardial ischemia reperfusion injury (MIRI). In the present study, we investigated whether low-dose rosuvastatin and fasudil, separately not possessing cardioprotection, express cardioprotective effects when combined. The isolated rat hearts underwent 30 min global ischemia and 120 min reperfusion.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
January 2014
The logical range of laser power density and optimum laser power density were explored for multi-element analysis of pulverized coal flow with laser-induced breakdown spectroscopy in the present paper. The range of laser energy was chosen from 20 to 160 mJ in the experiment. Pulverized coal less than 200 microm in diameter of particles fell freely through feeder outlet and the rate of flow was controlled by screw feeder.
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