We describe 3 cases of desmoplastic nevus with special emphasis on some repetitive dermoscopic and histopathologic features, which-if confirmed on larger series-could allow to identify desmoplastic nevus as a specific clinicopathologic entity within the spectrum of acquired melanocytic nevi.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/DAD.0b013e3181a9f0ee | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Role of Targeted Sequencing in Routine Diagnostics of Spitz Melanocytic Neoplasms-An Analysis of 70 Cases.
J Cutan Pathol
February 2025
Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Article Synopsis
- The Spitz group of melanocytic tumors should ideally include those with specific genomic changes like kinase receptor fusions and HRAS mutations, while traditional melanoma markers like BRAF mutations indicate a different diagnosis.
- A study involving 70 melanocytic tumors utilized targeted sequencing to differentiate between Spitz and conventional melanomas and clarify their classifications.
- The findings revealed substantial discrepancies in initial diagnoses, with 34% of cases having differing outcomes after molecular analysis, highlighting the need for genetic testing to improve diagnostic reliability in challenging cases.
Perineuriomatous Melanocytic Nevi: A Case Series of Four Cases.
J Cutan Pathol
February 2025
Department of Pathology, University of Arkansas for Medical Science, Little Rock, Arkansas, USA.
Background: Melanocytic tumors with perineuriomatous differentiation may pose diagnostic challenges. This study explores characteristics of perineuriomatous melanocytic nevi, an entity merging features of perineurioma and melanocytic nevi. The aim is to elucidate histopathological features of perineuriomatous nevi to allow dermatopathologists to recognize them and differentiate them from other spindle cell lesions.
View Article and Find Full Text PDFComparison of Clinicopathological Findings of Spitz Nevus in Pediatric and Adult Patients.
Turk Arch Pediatr
January 2024
Department of Dermatology, Hassa State Hospital, Hatay, Turkey.
Article Synopsis
- The study aims to analyze demographic and clinicopathological characteristics of patients with Spitz nevus, focusing on differences based on age and lesion location.
- Researchers reviewed the cases of 32 patients from 2010 to 2020, finding that more females were affected, with most lesions occurring on the upper extremities, particularly in children.
- Results showed distinct histological subtypes based on age: in children, the pigmented and compound variants were most common, while in adults, the desmoplastic variant prevailed, highlighting a need for further research with larger sample sizes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!