The presence of the enteroaggregative Escherichia coli (EAEC) virulence genes aatA, aap, and aggR was assayed in strains of different diarrheagenic E. coli pathotypes and nonpathogenic E. coli. The dispersin-encoding gene (aap) was detected in EAEC, diffusely adherent E. coli, and nonpathogenic E. coli, demonstrating that molecular diagnostics of EAEC based on aap detection may identify non-EAEC strains.
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http://dx.doi.org/10.1016/j.diagmicrobio.2009.05.011 | DOI Listing |
Front Microbiol
June 2020
Laboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.
Dispersin is a 10.2 kDa-immunogenic protein secreted by enteroaggregative (EAEC). In the prototypical EAEC strain 042, dispersin is non-covalently bound to the outer membrane, assisting dispersion across the intestinal mucosa by overcoming electrostatic attraction between the AAF/II fimbriae and the bacterial surface.
View Article and Find Full Text PDFDiagn Microbiol Infect Dis
September 2009
Laboratório de Bacteriologia, Instituto Butantan, São Paulo, SP, 05503-900, Brazil.
The presence of the enteroaggregative Escherichia coli (EAEC) virulence genes aatA, aap, and aggR was assayed in strains of different diarrheagenic E. coli pathotypes and nonpathogenic E. coli.
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