In this journal, Vyazovskiy et al. reported deoxyglucose data that they interpreted as supporting the Tononi and Cirelli hypothesis that cerebral metabolic rate (CMR) increases across waking. We summarize contradictory PET-deoxyglucose data that show CMR is the same in the morning and evening and that it decreases rather than increases after a night of sleep deprivation. We propose an alternative model of CMR-sleep homeostasis relations that points to novel experiments.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795118 | PMC |
| http://dx.doi.org/10.1016/j.brainresbull.2009.07.017 | DOI Listing |
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