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What's new about osmotic regulation of glycerophosphocholine. | LitMetric
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What's new about osmotic regulation of glycerophosphocholine.

Morgan Gallazzini Maurice B Burg

Physiology (Bethesda)

Department of Health and Human Services, Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

Published: August 2009

Glycerophosphocholine is an abundant renal medullary organic osmolyte that protects renal medullary cells from the high interstitial concentrations of NaCl and urea to which they are normally exposed. We consider the metabolism of glycerophosphocholine, its osmotic regulation, and the recently discovered molecular identity of the enzymes that osmoregulate its abundance.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943332PMC
http://dx.doi.org/10.1152/physiol.00009.2009DOI Listing

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