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http://dx.doi.org/10.1024/1661-8157.98.16.859 | DOI Listing |
BMC Infect Dis
December 2024
Institute of Biotechnology, Addis Ababa University P.O.Box.1176, Addis Ababa, Ethiopia.
Background: Early detection and treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP) could reduce the risk of developing life-threatening sepsis in childhood. However, little is known about sepsis caused by CRKP in children under-5 in developing countries. This study aimed to determine the epidemiology, antimicrobial resistance profile, associated risk factors and management of CRKP in children under-5 with sepsis in Ethiopia.
View Article and Find Full Text PDFInfect Drug Resist
December 2024
Centre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.
Objective: To compare the performance of a new chemiluminescence method with that of the traditional colloidal gold method for cryptococcal antigen (CrAg) detection.
Methods: Cryptococcosis is a global invasive mycosis associated with significant morbidity and mortality. Cryptococcal antigen (CrAg) testing from serum and cerebrospinal fluid (CSF) has been regarded as the gold standard for early diagnosis.
Am J Perinatol
December 2024
Obstetrics and Gynecology, Medical University of South Carolina, Charleston, United States.
Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and invasive pneumococcal disease among adults in the United States, with higher rates of disease occurring among individuals with chronic medical and immunocompromising conditions. Pregnant individuals, especially those with co-morbid conditions, are also at increased risk of infection due to S. pneumoniae due to physiologic and immunologic changes in pregnancy.
View Article and Find Full Text PDFRinsho Shinkeigaku
December 2024
Department of Neurology, Ichinomiya-Nishi Hospital.
A 52-year-old woman presented with the subacute onset of pantalgia, fever and consciousness disturbance. MRI revealed widespread symmetrical high-intensity areas along the sulci in both cerebral hemispheres on diffusion-weighted imaging (DWI). Rheumatoid meningitis was suspected based on elevated levels of anti-cyclic citrullinated peptide antibodies (ACPA) in both serum and cerebrospinal fluid (CSF), as well as an elevated ACPA index.
View Article and Find Full Text PDFCrit Rev Oncol Hematol
December 2024
Center for Clinical Investigation, INSERM U1434, Strasbourg University, 1 Avenue Molière, Strasbourg 67098, France; Neurology Department, Strasbourg University Hospitals, 1 Avenue Molière, Strasbourg 67098, France. Electronic address:
The ever-increasing use of immune checkpoint inhibitors (ICIs) has significantly improved cancer management, but at the cost of frequent immunologic side effects. Among them, neurologic immune-related adverse events (nirAEs) are less common but pose a challenge to clinicians due to their severity, heterogeneous nature and nonspecific clinical presentation, making diagnosis complex. The prognosis of these nirAEs, especially those related to the central nervous system (CNS), correlates with their rapid recognition and therapeutic management.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!