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AI in Hepatology: Revolutionizing the Diagnosis and Management of Liver Disease.
J Clin Med
December 2024
Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA.
The integration of artificial intelligence (AI) into hepatology is revolutionizing the diagnosis and management of liver diseases amidst a rising global burden of conditions like metabolic-associated steatotic liver disease (MASLD). AI harnesses vast datasets and complex algorithms to enhance clinical decision making and patient outcomes. AI's applications in hepatology span a variety of conditions, including autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, MASLD, hepatitis B, and hepatocellular carcinoma.
View Article and Find Full Text PDFCorrelation Between Clinical Indicators and Liver Pathology in Children with Chronic Hepatitis B.
Biomedicines
December 2024
Medical School of Chinese PLA, Beijing 100853, China.
Chronic hepatitis B (CHB) in children presents a significant global health challenge, with liver inflammation and fibrosis being critical concerns for disease progression and long-term outcomes. This retrospective study analyzed 1629 pediatric CHB patients from the Fifth Medical Center of Chinese PLA General Hospital, spanning from January 2000 to December 2021. Liver biopsies were performed to assess the severity of liver inflammation and fibrosis, which were graded using the Scheuer scoring system.
View Article and Find Full Text PDFA Comprehensive Health Screening Program Reveals the Prevalence of and Risk Factors for Age-Related Macular Degeneration: A Cross-Sectional Analysis.
Biomedicines
November 2024
Department of Ophthalmology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
: We investigated the prevalence of age-related macular degeneration (AMD) and associated risk factors in Korean subjects who underwent comprehensive health screening examinations. : This single health screening center-based cross-sectional study included a total of 73,574 consecutive participants older than 30 years who underwent a health screening examination, including fundus photography, between October 2003 and December 2010. Weighted prevalence and risk factors for AMD were evaluated.
View Article and Find Full Text PDFDevelopment of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective Cohort Study.
JMIR Public Health Surveill
December 2024
Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine, Chinese Academy of Sciences, 1 East Banshan Road, Hangzhou, 310022, China, 86 571-88122219.
Background: Liver cancer continues to pose a significant burden in China. To enhance the efficiency of screening, it is crucial to implement population stratification for liver cancer surveillance.
Objective: This study aimed to develop a simple prediction model and risk score for liver cancer screening in the general population, with the goal of improving early detection and survival.
Evaluation of Three Viral Capsid Integrity qPCR Methods for Wastewater-Based Viral Surveillance.
Food Environ Virol
January 2025
School of Environmental and Natural Sciences, Bangor University, Bangor, Gwynedd, LL57 2UW, UK.
Article Synopsis
- CI-qPCR assays provide a viable alternative to traditional cell culture methods for assessing virus viability in wastewater, specifically focusing on human pathogens.
- The study evaluated three CI-qPCR methods (Crosslinker, TruTiter, and PMAxx) on various viruses like HAdV and SARS-CoV-2, revealing differences in sensitivity and effectiveness between them.
- Findings suggest that while PMAxx struggled with detecting certain heat-inactivated viruses, both PMAxx and TruTiter successfully identified intact viruses in wastewater, showing promise for improving public health monitoring and response to emerging viral threats.
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