Aqueous methods for the preparation of 5'-substituted guanosine derivatives. | LitMetric

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Aqueous methods for the preparation of 5'-substituted guanosine derivatives. | LitMetric

Aqueous methods for the preparation of 5'-substituted guanosine derivatives.

Paul Brear Gemma R Freeman Mark C Shankey Milena Trmcić David R W Hodgson

Chem Commun (Camb)

Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, UKDH1 3LE.

Published: September 2009

* Our focus was on producing various 5'-substituted guanosine derivatives.
* This approach simplifies the preparation process in the field of chemical synthesis.

We have developed simple, aqueous strategies, that avoid the use of protecting groups and chromatography, for the preparation of a series of 5'-substituted guanosine derivatives.

Download full-text PDF	Source
http://dx.doi.org/10.1039/b908727c	DOI Listing

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