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Histopathologic confirmation of subchondral fracture in symptomatic pre-collapse osteonecrosis of the femoral head with bone marrow edema on magnetic resonance imaging.
Skeletal Radiol
November 2024
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Objective: The presence of bone marrow edema on magnetic resonance imaging (MRI) in pre-collapse osteonecrosis of the femoral head is suggested to be a sign of occult subchondral fracture; however, to our knowledge, there are no histopathological studies verifying this. This study aimed to histopathologically verify the presence of subchondral fracture at the lateral necrotic boundary in symptomatic pre-collapse osteonecrosis of the femoral head with bone marrow edema on MRI.
Materials And Methods: Of 149 consecutive necrotic femoral heads resected during total hip arthroplasty at our hospital from January 2019 to June 2024, we included 13 femoral heads that did not show apparent collapse on preoperative radiographs and exhibited bone marrow edema on MRI.
The Application of Magnetic Resonance Imaging in the Early and Accurate Diagnosis of Hip Joint Avascular Necrosis.
Cureus
September 2024
Radiodiagnosis, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Article Synopsis
- Avascular necrosis (AVN) is the death of bone tissue due to disrupted blood supply, often seen in the femoral head, and this study investigates MRI's role in diagnosing it early.
- Conducted at a hospital in India, the research analyzed 30 patients with hip pain, comparing diagnoses made via plain radiographs and MRI; MRI correctly identified AVN in all cases, while radiographs missed many.
- The study concludes that relying only on X-rays can overlook critical stages of AVN; MRI is superior in detecting the condition early due to its advanced imaging capabilities.
Updates in non-neoplastic orthopaedic pathology: what you don't know can hurt you!
J Clin Pathol
September 2024
Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA
Article Synopsis
- Most research in surgical pathology tends to focus on rare tumors, while average pathologists deal with common non-neoplastic orthopedic conditions daily, indicating a gap in knowledge for these frequent cases.* -
- Intraoperative consultations, especially for revision arthroplasty infections, are vital, as pathologists help determine the need for antibiotic spacers based on their assessments.* -
- Recent literature highlights the importance of thorough examination of orthopedic specimens, as it can lead to significant insights into conditions like avascular necrosis and even early diagnosis of diseases like cardiac amyloidosis.*
Hypophosphatemic osteomalacia induced by intravenous iron therapy: a case report.
Joint Bone Spine
September 2023
Rheumatology Department, Centro Hospitalar Universitário do S. João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal; Department of Medicine, Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Objective: Osteomalacia is an uncommon, overlooked and debilitating metabolic bone disease with numerous aetiologies. Herein, we report an atypical cause of osteomalacia - intravenous iron therapy.
Methods: Description of a case report of hypophophatemic osteomalacia induced by ferric carboxymaltose infusions.
Differences in magnetic resonance findings between symptomatic and asymptomatic pre-collapse osteonecrosis of the femoral head.
Eur J Radiol
March 2019
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address:
Purpose: The purpose of this study was to assess the differences in magnetic resonance (MR) findings between the symptomatic and asymptomatic pre-collapse stage of osteonecrosis of the femoral head (ONFH).
Materials And Methods: This study reviewed 123 consecutive hips in 91 patients in the pre-collapse stage of ONFH based on plain radiographic findings. These 123 hips were divided into symptomatic and asymptomatic groups according to the pain domain score in the Harris hip score system.
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