Management of migraine headache had once been considered as one of the least satisfying conditions to treat. Fortunately, developments in our understanding of the disorder and available treatment options have revolutionized therapy and greatly improved outcomes of affected patients. Two major factors are the development of a treatment "toolkit" for patients and a mutual setting of goals by the patient and clinician. The treatment "toolkit" includes several very important elements, foremost among them is patient education. This critical component provides a logical basis of therapy by helping patients understand the disorder and aiding deployment of the toolkit. This knowledge empowers patients to optimize treatment outcome and minimize the headache-related disability that drives them to seek treatment. Setting of goals for both acute and preventive care, providing behavioral and lifestyle advice, offering appropriate medications for acute attacks and headache prevention, and incorporating strategies for effective use enhance success. Monitoring outcome can focus the management and help more patients attain effective care rapidly. Employing such an approach can turn therapy into a process that proves to be satisfying to both patient and clinician.
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http://dx.doi.org/10.3810/pgm.11.2003.suppl30.170 | DOI Listing |
J Headache Pain
January 2025
School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia.
Background: Migraine is the most common complex neurological disorder, affecting over a billion people worldwide. Neurogenic inflammation has long been recognized as a key factor in the pathophysiology of migraine though little research has been directed to investigating whether inflammation is greatest in migraine with aura or without, and whether inflammation is a permanent state in migraine or whether is an event related transitory state. Thus, the primary aim of this single-centre, retrospective study was to explore the potential clinical utility of the Serial Systemic Immune-Inflammatory Indices (SSIIi) as a comparative measure of duration and severity of inflammation derived from routine blood cell counts in migraine patients with aura and no-aura both within an acute inpatient setting and as outpatients.
View Article and Find Full Text PDFNeurogastroenterol Motil
January 2025
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Investigations into mechanisms of cyclic(al) vomiting syndrome (CVS) began at the bedside more than a century ago. The modern era started with the formation of the Cyclic Vomiting Syndrome Association in 1993 that helped initiate robust efforts in education, advocacy, family physician conferences, scientific symposia, dedicated clinical programs, therapeutic guidelines, and research. Even today, bedside clues continue to emerge with the recent description of cannabinoid hyperemesis syndrome (CHS) and subsequent evidence of a perturbed endocannabinoid system.
View Article and Find Full Text PDFNeurology
February 2025
Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Germany.
Background And Objectives: The Chordate System administers kinetic oscillation stimulation (K.O.S) into the nasal cavity thereby potentially modulating the activity of trigemino-autonomic reflex.
View Article and Find Full Text PDFJ Med Life
November 2024
College of Medicine and Surgery, Taibah University, Madinah, Kingdom of Saudi Arabia.
Migraine is a burdensome primary headache disorder with a global prevalence ranging from 15-18%. Our study aimed to assess the knowledge among primary healthcare physicians regarding migraine and evaluate whether their management practices align with current advances. This descriptive cross-sectional study included 212 primary healthcare physicians working in Al-Madinah Al-Munawarah, Kingdom of Saudi Arabia.
View Article and Find Full Text PDFCureus
December 2024
Neurology, Tecnológico de Monterrey, Monterrey, MEX.
Isolated ophthalmoplegia as an anti-glutamic acid decarboxylase 65 (anti-GAD65) antibody-associated neurological syndrome is rare. We present a case of a 22-year-old pregnant Hispanic female patient who presented initially with a left oculomotor nerve palsy following an emergency department (ED) visit for migraine headache. Brain imaging was done with no important findings.
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