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Addressing the malaria drug resistance challenge using flow cytometry to discover new antimalarials. | LitMetric

A new flow cytometry method that uses an optimized DNA and RNA staining strategy to monitor the growth and development of the Plasmodium falciparum strain W2mef has been used in a pilot study and has identified Bay 43-9006 1, SU 11274 2, and TMC 125 5 as compounds that exhibit potent (<1 microM) overall and ring stage in vitro antimalarial activity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131497PMC
http://dx.doi.org/10.1016/j.bmcl.2009.07.095DOI Listing

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