Host genetic diversity plays an important role in buffering populations against pathogens. We characterized the allelic diversity at the second exon of the b (DRB-2) chain of the major histocompatibility complex class II (MHC-II) locus in a population of Iberian red deer (Cervus elaphus hispanicus) and its impact on parasitism by macroparasites, on a microparasite causing tuberculosis, and on relevant life history traits (spleen size and body condition). No DRB-2 haplotype conferred general resistance or susceptibility against all parasites. However, specific significant correlations were found between some DRB-2 haplotypes and specific parasites. We also detected associations between DRB-2 haplotypes and body condition and spleen size after controlling for body size, sex and age. Our results evidenced a functional significance of MHC-II genes in the defence of Iberian red deer against parasites. These results also support a role of MHC-II as a fitness-enhancing genetic element which can be mediated by parasite effects on life traits with a genetic basis. We conclude that MHC immunogenetic studies may assess management decisions in Iberian red deer because (i) loss of genetic diversity may lead to increased disease occurrence, and (ii) MHC genes are ecologically relevant since they underlie host infection rates and life history traits.
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http://dx.doi.org/10.1016/j.meegid.2009.07.010 | DOI Listing |
Zoonoses Public Health
December 2024
Departamento de Sanidad Animal, Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, Córdoba, Spain.
Background: West Nile virus (WNV) is the most widely distributed mosquito-borne flavivirus. Over the past decade, its spread across Europe has raised significant concerns for both public and animal health. Although WNV exposure has been evidenced in various wild mammal species in Spain, no seroepidemiological studies have been conducted on this flavivirus in wild lagomorphs so far.
View Article and Find Full Text PDFAnimals (Basel)
November 2024
Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), Departamento de Sanidad Animal, UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, 14014 Córdoba, Spain.
is a vector-borne zoonotic bacterium that causes tularemia, a disease of great importance for animal and public health. Although wild lagomorphs are considered one of the major reservoirs of this bacterium, information about the circulation of in European wild rabbit () and Iberian hare () populations in Europe is still very limited. In Spain, is present in northern central regions, with recurrent outbreaks occurring annually.
View Article and Find Full Text PDFParasitol Res
December 2024
Animal Health Department, Faculty of Veterinary Medicine, Universidad Complutense of Madrid, Madrid, Spain.
Piroplasmids are vector-borne hemoprotozoan parasites belonging to the phylum Apicomplexa that are of veterinary and medical importance. Wild carnivores are hosts for diverse piroplasmids, some of which are highly pathogenic for domestic dogs and cats. A large-scale survey including samples from 244 individuals belonging to eleven different species that were opportunistically obtained between 1993 and 2015 in four Autonomous Regions in Spain were tested for piroplasmid DNA with two different nested-PCR assays targeting the 18S rRNA gene.
View Article and Find Full Text PDFZootaxa
April 2024
IEO-CSIC. Centro Oceanográfico de Gijón (COG-IEO); Avda Principe de Asturias 72bis; 33212 Gijón; Spain; Departamento de Zoología y Antropología Física. Universidad de Alcalá; Madrid; Spain.
The genus Biemna currently includes fifty-eight valid species distributed worldwide with a wide depth range. In this paper, we describe a new species of this genus, Biemna begonae sp. nov.
View Article and Find Full Text PDFAnimals (Basel)
October 2024
Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), Departamento de Sanidad Animal, UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, 14071 Córdoba, Spain.
The European Food Safety Authority has recently listed Q fever as a priority for setting up a coordinated surveillance system. Although Spain is the country with the highest human incidence of the disease in the European Union, updated data on in ruminants are still limited. A total of 780 serum samples from small ruminants and 605 sera from wild ruminants were collected in the Mediterranean ecosystems of southern Spain during the period 2015-2023.
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