Analysis of contemporary clinical and experimental studies evidences that intraoperative microemboli considerably contribute to the development of postoperative deliria and cognitive disorders. A number of studies have shown that left temporal and occipital structures are especially vulnerable to intraoperative ischemia. It is important that neurological cases of ischemia of the former brain regions are frequently characterized by transient psychoses and hypomnesia. Approaches to preventing intraoperative microembolism and associated neurological complications need further research.
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J Med Internet Res
January 2025
Department of Anesthesiology, Daping Hospital, Army Medical University, Chongqing, China.
Background: Recent research has revealed the potential value of machine learning (ML) models in improving prognostic prediction for patients with trauma. ML can enhance predictions and identify which factors contribute the most to posttraumatic mortality. However, no studies have explored the risk factors, complications, and risk prediction of preoperative and postoperative traumatic coagulopathy (PPTIC) in patients with trauma.
View Article and Find Full Text PDFJMIR Res Protoc
January 2025
Orthopedics and Trauma Surgery, University Hospital Düsseldorf, Düsseldorf, Germany.
Background: An aging population in combination with more gentle and less stressful surgical procedures leads to an increased number of operations on older patients. This collectively raises novel challenges due to higher age heavily impacting treatment. A major problem, emerging in up to 50% of cases, is perioperative delirium.
View Article and Find Full Text PDFJ Adv Nurs
January 2025
School of Nursing and Midwifery, Centre for Quality and Patient Safety Research, Institute for Health Transformation, Deakin University, Geelong, Victoria, Australia.
Aim(s): To identify and synthesise available evidence about regular medication management processes, from preadmission to discharge from hospital, in patients with cancer undergoing surgery.
Design: Mixed-methods systematic review.
Methods: Studies published from inception of each database until February 2023 were screened, utilising four main search concepts.
Front Med (Lausanne)
January 2025
Department of Orthopaedics, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Background: Various factors contribute to postoperative delirium (POD) in elderly patients undergoing hip fracture surgeries. Sarcopenia was defined as the progressive loss of skeletal muscle mass and strength associated with aging. The aim of this study was to explore the prevalence of POD and sarcopenia in geriatric patients undergoing hip fracture surgeries and to investigate the correlation between preoperative sarcopenia and POD.
View Article and Find Full Text PDFBMC Pharmacol Toxicol
January 2025
Department of general medicine, Ordos Central Hospital, Ordos School of Clinical Medicine, Inner Mongolia Medical University, 23 Yijinhuoluo West Street, Dongsheng District, Ordos, Inner Mongolia, 017000, PR China.
Objectives: We conducted a meta-analysis to investigate the effect of dexmedetomidine on postoperative delirium in elderly orthopedic surgery patients.
Methods: A meta-analysis was conducted to identify randomized controlled trials of dexmedetomidine in elderly patients undergoing orthopedic surgery. The data was published on October 25, 2024.
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