This month's Genome Watch discusses the applications of whole-genome comparative genomics and reverse vaccinology for two life-threatening pathogens
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097615 | PMC |
| http://dx.doi.org/10.1038/nrmicro1898 | DOI Listing |
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Prediction of antimicrobial susceptibility of pneumococci based on whole-genome sequencing data: a direct comparison of two genomic tools to conventional antimicrobial susceptibility testing.
J Clin Microbiol
December 2024
Laboratory of Clinical Microbiology, KU Leuven, Department of Microbiology, Immunology and Transplantation, Leuven, Flanders, Belgium.
Determination of antimicrobial resistance (AMR) in pneumococcal isolates is important for surveillance purposes and in a clinical context. Antimicrobial susceptibility testing (AST) of pneumococci is complicated by the need for exact minimal inhibitory concentrations (MICs) of beta-lactam antibiotics. Two next-generation sequencing (NGS) analysis tools have implemented the prediction of AMR in their analysis workflow, including the prediction of MICs: Pathogenwatch (https://pathogen.
View Article and Find Full Text PDFSleep Health Patterns in Romania: Insights from a Nationwide Cross-Sectional Online Survey.
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October 2024
RoNeuro Institute for Neurological Research and Diagnostics, 400364 Cluj-Napoca, Romania.
Background: Sleep is one of the most essential processes for sustaining cognitive, emotional, and physical health across all age groups. Insomnia or inadequate sleep significantly impacts health and poses economic burdens due to increased healthcare costs and reduced productivity.
Objectives And Methods: This study aimed to investigate sleep quality in the Romanian active population using an online survey incorporating the Pittsburgh Sleep Quality Index (PSQI).
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Front Neurol
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Center of Encephalopathy, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
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Relationships between screen time and childhood attention deficit hyperactivity disorder: a Mendelian randomization study.
Front Psychiatry
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School of Management, Beijing University of Chinese Medicine, Beijing, China.
Background: In previous observational studies and meta-analyses, childhood attention deficit hyperactivity disorder (ADHD) is found to have a significant association with screen time. However, the causal associations between them remain unclear.
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