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Trends of Representation of Women in Professional Medical Societal Leadership in the United States and Europe.
JACC Adv
February 2025
Department of Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
Background: There continue to be significant gender disparities with women being underrepresented in medical professional society leadership roles, despite more women entering medical school.
Objectives: This study aimed to elucidate the pattern of representation of women in medical society presidential positions in the United States and Europe over the past 50 years. It further examines gender-related trends in the field of cardiology and among medical trainees.
Game changing electoral reforms and party system change? An analysis of the 2020 national assembly election in South Korea.
Heliyon
January 2025
School of International Studies, Hanyang University, 222Wangsimni-ro, Seongdong-gu, Seoul, 04763, Republic of Korea.
The article analyses the 2020 National Assembly election in South Korea. It was the first legislative election held after President Park Geun-hye had been successfully impeached, and removed from office, in March 2017. The 2020 election was also the first election after important changes to the electoral law were made in 2019.
View Article and Find Full Text PDFNivolumab plus ipilimumab versus nivolumab in microsatellite instability-high metastatic colorectal cancer (CheckMate 8HW): a randomised, open-label, phase 3 trial.
Lancet
January 2025
Istituto Oncologico Veneto IOV-IRCCS, Padua, Italy.
Background: CheckMate 8HW prespecified dual primary endpoints, assessed in patients with centrally confirmed microsatellite instability-high or mismatch repair-deficient status: progression-free survival with nivolumab plus ipilimumab compared with chemotherapy as first-line therapy and progression-free survival with nivolumab plus ipilimumab compared with nivolumab alone, regardless of previous systemic treatment for metastatic disease. In our previous report, nivolumab plus ipilimumab showed superior progression-free survival versus chemotherapy in first-line microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer in the CheckMate 8HW trial. Here, we report results from the prespecified interim analysis for the other primary endpoint of progression-free survival for nivolumab plus ipilimumab versus nivolumab across all treatment lines.
View Article and Find Full Text PDFExperiences and overall impact reported by people living with obesity: results from a multinational study.
SAGE Open Med
January 2025
Endocrinology Diabetes, Metabolism, and Obesity Medicine, Obesity, Endocrine, and Metabolism Center (OEMC), King Fahad Medical City (KFMC), Riyadh, Saudi Arabia.
Objectives: To explore the impact of obesity on clinical outcomes, health-related quality of life, emotional well-being, and work productivity in people/patients with obesity across six countries by body mass index and the presence of complications.
Methods: Adelphi Real World Obesity Disease Specific Programme™ captured data related to physicians and their consulting people/patients with obesity on a weight management program or anti-obesity medication in Brazil, Canada, China, Japan, Kingdom of Saudi Arabia, and the United Arab Emirates from April to December 2022. Physicians reported data for up to eight qualifying people/patients with obesity.
Correlation between rrs gene mutations and amikacin resistance in Mycobacterium abscessus: implications for fitness cost and clinical prevalence.
J Antimicrob Chemother
January 2025
Institutes of Physical Science and Information Technology, Anhui University, Hefei, Anhui 230601, China.
Objectives: Amikacin is crucial for treating Mycobacterium abscessus (Mab) infections, with resistance primarily attributed to rrs gene mutations. The correlation between specific mutations and amikacin susceptibility, along with the associated fitness cost, requires further investigation.
Methods: We isolated spontaneous amikacin-resistant mutants in vitro and identified their mutation sites in the rrs gene via Sanger sequencing, which were then compared with existing reports.
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