Uveitis in childhood: an Italian clinical and epidemiological study.

Ocul Immunol Inflamm

Department of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Rome, Italy.

Published: October 2009

Purpose: To investigate demographics, causes, features, and visual outcomes of pediatric uveitis.

Methods: Retrospective cohort study including 257 patients younger than 16 years.

Results: Mean age at onset of uveitis was 8.54 +/- 3.98 years; 54.5% of the patients were girls. Anterior uveitis occurred in 47.8%, intermediate in 19.4%, posterior in 24.9%, panuveitis in 7.8%. Ocular involvement was bilateral in 67.8%. Infectious uveitis represented 31% of all cases. Causes of severe visual loss were cataract, macular scars, macular edema/maculopathy, and secondary glaucoma. At follow-up 79.3% of eyes maintained a visual acuity between 20/32 and 20/20.

Conclusions: Uveitis is rarer in children than in adults. Patients with anterior uveitis comprised the largest group. Posterior uveitis in the pediatric population has a lower incidence than some decades ago. Visual prognosis of pediatric uveitis is improving, owing to an earlier diagnosis and a correct treatment.

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http://dx.doi.org/10.1080/09273940802702561DOI Listing

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