AI Article Synopsis

  • Near-infrared (NIR) fluorescence can assist surgeons by providing real-time imaging during operations, improving the visibility of tissues.
  • The study presents a low-cost electronic circuit that can control LEDs for fluorescence measurements at frequencies up to 35 MHz, which helps enhance the quality of fluorescence images.
  • Details about the circuit design and components are made available online for others to access and utilize in related research.

Article Abstract

Near-infrared (NIR) fluorescence has the potential to provide surgeons with real-time intraoperative image-guidance. Increasing the signal-to-background ratio of fluorescent agents involves delivering a controllable excitation fluence rate of proper wavelength and/or using complementary imaging techniques such as FLIM. In this study we describe a low-cost linear driver circuit capable of driving Light Emitting Diodes (LEDs) from DC to 35 MHz, at high power, and which permit fluorescence CW and lifetime measurements. The electronic circuit Gerber files described in this article and the list of components are available online at www.frangionilab.org.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719859PMC
http://dx.doi.org/10.1117/12.779196DOI Listing

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