The aim of this case report was to describe the clinical, ultrasonographic and postmortem findings in a goat with a mesothelioma. The most striking clinical sign was marked bilateral distension of the abdomen caused by ascites. Other signs included abnormal general condition, weight loss, hypothermia and increased heart rate. Ultrasonographic examination revealed accumulation of a massive amount of hypoechoic fluid in the abdominal cavity and nodular lesions on the peritoneum, omentum and wall of the omasum. Based on the clinical and ultrasonographic findings, a tentative diagnosis of ascites attributable to neoplasia was made, and the goat was euthanized. Postmortem examination confirmed the diagnosis, and based on the results of histological examination, a mesothelioma was diagnosed.
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