Image restoration and simplification methods that respect important features such as edges play a fundamental role in digital image processing. However, known edge-preserving methods like common nonlinear diffusion methods tend to round vertices for large diffusion times. In this paper, we adapt the diffusion tensor for anisotropic diffusion to avoid this effects in images containing rotated and sheared rectangles, respectively. In this context, we propose a new method for estimating rotation angles and shear parameters based on the so-called structure tensor. Further, we show how the knowledge of appropriate diffusion tensors can be used in variational models. Numerical examples including orientation estimation, denoising and segmentation demonstrate the good performance of our methods.
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http://dx.doi.org/10.1109/TIP.2009.2028934 | DOI Listing |
Alzheimers Dement
December 2024
University of Washington, Seattle, WA, USA.
Background: Leveraging non-invasive ultra-high field, 7 Tesla (7T) MRI, with increased signal-to-noise ratio and improved soft tissue contrast afforded by 7T allows us to accurately map tissue microstructure. We aim to use 7T MR Elastography (MRE), 7T Diffusion Tensor Imaging (DTI), 3T amyloid-PET, and Preclinical Alzheimer Cognitive Composite (PACC) score to determine the relationships between these metrics in a cohort of older individuals with either normal cognition (CN), mild cognitive impairment (MCI), or Alzheimer's Disease (AD).
Methods: 7T MRE, 7T DTI, 3T PET (Fig.
Alzheimers Dement
December 2024
Institute of Neuropathology, Fukushimura Hospital, Toyohashi, Japan.
Background: The Fukushimura (welfare village), located in Toyohashi city, Japan, is a unique complex of various nursing home facilities including dementia homes, Day-care houses, homes for disabled and mentally retarded, and the Fukushimura Hospital. This village is totally managed by private sector, the Sawarabi Medical Cooperative. About 800 elderly people reside in this area.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Huashan Hospital, Fudan University, Shanghai, China.
Background: Although glymphatic function is involved in Alzheimer's disease (AD), its potential for tracking the pathological and clinical progression of AD and its sequential association with core AD biomarkers is poorly understood.
Method: Whole-brain glymphatic activity was measured by diffusion tensor image analysis along the perivascular space (DTI-ALPS) in participants with AD (n = 47), mild cognitive impairment (n = 137), and normal controls (n = 235) from the Alzheimer's Disease Neuroimaging Initiative.
Result: Decreased ALPS-index was observed in AD dementia, prodromal AD, and preclinical AD patients.
Alzheimers Dement
December 2024
NYU Grossman School of Medicine, New York, NY, USA.
Background: We examined racial differences between measures of limbic white matter tracts and objective sleep parameters in cognitively unimpaired older-adults.
Method: This cross-sectional study included 170 community-dwelling cognitively unimpaired older-adults (mean±SD: age = 67.2±5.
Alzheimers Dement
December 2024
Texas A&M University Health, Bryan, TX, USA.
Background: Our studies show that the small non-coding RNA, mir20a-3p, is neuroprotective for stroke in the acute phase and also attenuates long term cognitive decline in middle-aged female rats. Cognitive decline due to vascular diseases, such as stroke, is associated with secondary neurodegeneration in cortex and limbic structures. In this study, we assessed the volume of white matter, ventricles and regional diffusion-weighted MR imaging measures to delineate pathological tissue characteristics from the postmortem brain of stroke rats.
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