Introduction: Many case reports have documented the successful use of titanium miniscrews for orthodontic anchorage. However, the literature lacks a well-controlled study examining the effect of miniscrew diameter on anchorage force resistance. The purpose of this in-vitro study was to compare the force resistance of larger-diameter monocortical miniscrews to smaller-diameter monocortical miniscrews; and to compare the force resistance of larger-diameter monocortical miniscrews to smaller-diameter bicortical miniscrews.
Methods: Ninety-six titanium alloy screws were placed into 24 hemisected maxillary and 24 hemisected mandibular specimens between the first and second premolars. Specimens were randomly and evenly divided into 2 groups. In the first group, 24 large-diameter screws (2.5 x 17 mm) and with 24 small-diameter screws (1.5 x 15 mm) were placed monocortically. In the second group, 24 large-diameter screws (2.5 x 17 mm) were placed monocortically and 24 small-diameter screws (1.5 x 15 mm) were placed bicortically. All screws were subjected to tangential force loading perpendicular to the miniscrew with lateral displacement of 0.6 mm. Statistical analyses, including the paired-samples t test and the 2-samples t test, were used to quantify screw force-deflection characteristics. One-way analysis of variance (ANOVA) with the post-hoc Tukey studentized range test was used to determine any significant differences, and the order of those differences, in force anchorage values among the 3 screw types at maxillary and mandibular sites.
Results: Mean mandibular and maxillary anchorage force values of the 2.5-mm monocortical screws were significantly greater than those of the 1.5-mm monocortical screws (P <0.01). No statistically significant differences in mean mandibular anchorage force values were found between the 2.5-mm monocortical screws and the 1.5-mm bicortical screws. However, mean maxillary anchorage force values of the 1.5-mm bicortical screws were significantly greater than those of the 2.5-mm monocortical screws (P <0.01). Data analyzed with 1-way ANOVA with the post-hoc Tukey studentized range tests indicated that the mean mandibular and maxillary force values of the 2.5-mm monocortical screws and the 1.5-mm bicortical screws were significantly greater than those of the 1.5-mm monocortical screws (P <0.01). Based on the 2-samples t test, mean anchorage force values at mandibular sites were significantly greater than at maxillary sites for the 2.5-mm monocortical screws and the 1.5-mm monocortical screws. There were no statistically significant differences in mean anchorage force values between maxillary and mandibular sites for the 1.5-mm bicortical screws.
Conclusions: In vitro, larger-diameter (2.5 mm) monocortical screws provide greater anchorage force resistance than do smaller-diameter (1.5 mm) monocortical screws in both the mandible and the maxilla. Smaller-diameter (1.5 mm) bicortical screws provide anchorage force resistance at least equal to larger-diameter (2.5 mm) monocortical screws. An alternative to placing a larger-diameter miniscrew for additional anchorage is a narrower bicortical screw.
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http://dx.doi.org/10.1016/j.ajodo.2007.07.031 | DOI Listing |
Sci Rep
January 2025
Department of Psychology, Faculty of Psychology and Sport Science, Justus Liebig University, Otto-Behaghel-Str. 10F, 35394, Gießen, Germany.
Adapting movements to rapidly changing conditions is fundamental for interacting with our dynamic environment. This adaptability relies on internal models that predict and evaluate sensory outcomes to adjust motor commands. Even infants anticipate object properties for efficient grasping, suggesting the use of internal models.
View Article and Find Full Text PDFJ Neurotrauma
January 2025
Department of Neurosurgery, the First Medical Centre, Chinese PLA General Hospital, Beijing, China.
Following traumatic brain injury (TBI), inhibition of the Na-K-Cl cotransporter1 (NKCC1) has been observed to alleviate damage to the blood-brain barrier (BBB). However, the underlying mechanism for this effect remains unclear. This study aimed to investigate the mechanisms by which inhibiting the NKCC1 attenuates disruption of BBB integrity in TBI.
View Article and Find Full Text PDFPhytomedicine
January 2025
Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. Electronic address:
Background: Staphylococcus aureus is an opportunistic pathogen capable of readily forming biofilms, which can result in life-threatening infections involving different organs. Sanguinarine are benzo[c]phenanthridine alkaloids extracted from the Sanguinaria canadensis L. (Papaveraceae), which have a wide range of biological activities.
View Article and Find Full Text PDFEpilepsia
January 2025
Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Clinical practice guidelines (CPGs) and consensus-based recommendations (CBRs) require considerable effort, collaboration, and time-all within the constraints of finite resources. Professional societies, such as the International League Against Epilepsy (ILAE), must prioritize what topics and questions to address. Implementing evidence-based care remains a crucial challenge in clinical practice.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.
Hydrogel-based sensors typically demonstrate conspicuous swelling behavior in aqueous environments, which can severely compromise the mechanical integrity and distort sensing signals, thereby considerably constraining their widespread applicability. Drawing inspiration from the multilevel heterogeneous structures in biological tissues, an antiswelling hydrogel sensor endowed with high strength, rapid self-recovery, and low swelling ratio was fabricated through a water-induced phase separation and coordination cross-linking strategy. A dense heterogeneous architecture was developed by the integration of "rigid" quadridentate carboxyl-Zr coordination bonds and "soft" hydrophobic unit-rich regions featuring π-π stacking and cation-π interactions into the hydrogels.
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