Restless legs syndrome (RLS) is one of the most common neurological diseases. Even though there is a large progress in its diagnosis, pathophysiology and treatment, it still remains recognised too rarely. It is elderly people who mostly suffer from restless legs syndrome, but it is established that the disease may begin in childhood. The aim of this study is to present the diagnostic criteria and differential diagnosis in cases of this syndrome, in children. Correct diagnosis of restless legs syndrome is a starting point for epidemiological studies on the incidence of RLS in children.
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BMJ Case Rep
January 2025
Internal Medicine, East Suffolk and North Essex NHS Foundation Trust Ipswich Hospital, Ipswich, UK.
This case report presents a complex medical scenario involving early 60s female patient with a history of chronic lymphocytic leukaemia (CLL) complicated by Evans syndrome, characterised by autoimmune haemolytic anaemia and immune thrombocytopenia. The patient had received various treatments, including steroids, rituximab, cyclosporine and acalabrutinib. The patient's neurological symptoms began around 3 years prior to presentation, with shaking of her right leg, followed by shaking of both hands, particularly the left hand.
View Article and Find Full Text PDFIn Vivo
December 2024
Department of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.;
Background/aim: Transient ischaemic attack (TIA) is characterised by a temporary neurological dysfunction resulting from focal ischaemia in the brain, spinal cord or retina without acute infarction. These episodes typically last less than 24 hours and are significant predictors of subsequent ischaemic strokes. Hypertension is a major risk factor for cerebrovascular events, and primary aldosteronism (PA) is recognised as a common cause of secondary hypertension.
View Article and Find Full Text PDFBMC Musculoskelet Disord
December 2024
Department of Orthopaedics, School of Medicine, Zhongda Hospital, Southeast University, No. 87 Ding Jia Qiao, Nanjing, 210009, Jiangsu, China.
Background: Osteosarcopenia is a geriatric syndrome associated with an increased risk of frailty, falls, fractures, disability, and death. Calf circumference (CC) has been used as a simple and practical skeletal muscle marker to diagnose sarcopenia. This study aimed to explore the relationship of calf circumference and osteoporosis (OP) and hip fractures (HF) in middle-aged and older adults.
View Article and Find Full Text PDFThis case report describes a unique presentation of May-Thurner syndrome (MTS) in a 28-year-old woman, characterized by the congenital bifurcation of the left common iliac vein (LCIV) into the outer (OLCIV) and inner (ILCIV) segments. Both veins experienced significant compression - OLCIV proximally and ILCIV medially - due to the overlying right common iliac artery (RCIA) and lumbar spine. The patient presented with bilateral spider veins, lower extremity swelling, pelvic discomfort, and bilateral leg cramping.
View Article and Find Full Text PDFMed J Armed Forces India
December 2024
Classified Specialist (Obst & Gynae), INHS Sandhani, Naval Station Karanja, Uran, Raigarh, India.
Peroneus longus ruptures are less common than ruptures of the peroneus brevis muscle and are seldom described in the literature. Ankle inversion injuries causing injury to the distal end of the peroneus longus muscle resulting in lateral compartment syndrome have been documented in the literature. We are presenting an unusual case of peroneal compartment syndrome with no overt ankle injury.
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