Involvement of the orbit and posterior segment of the eye in early-onset sarcoidosis may necessitate prompt and aggressive immunosuppressive treatment to prevent a poor visual outcome.
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Editorial: Basic, clinical, and translational studies of Yao syndrome and other NOD2 related diseases.
Front Immunol
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Division of Rheumatology, Allergy and Immunology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY, United States.
Blau syndrome mimics Takayasu's arteritis: Report of 2 cases with literature review.
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Department of Rheumatology and Immunology, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan Province, China.
Comprehensive clinical phenotype, genotype and therapy in Yao syndrome.
Front Immunol
October 2024
Division of Rheumatology, Allergy and Immunology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY, United States.
Article Synopsis
- Yao syndrome (YAOS) is an autoinflammatory disease linked to specific genetic variants, with this study analyzing a large group of adult patients diagnosed with related conditions.
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Towards New Anti-Inflammatory Agents: Design, Synthesis and Evaluation of Molecules Targeting XIAP-BIR2.
ChemMedChem
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Department, Normandie Univ, UNICAEN, CERMN, bd Becquerel, F-14000, Caen, Cedex, France.
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- XIAP is a protein that helps regulate cell survival and inflammation, and targeting it could benefit diseases like Crohn's disease and sarcoidosis.
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: A HERV Turn-On for Autoimmunity, Neurodegeneration, and Cancer?
Microorganisms
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Department of Biomedical Science, University of Sassari, 07100 Sassari, Italy.
Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that, over millions of years, became integrated into the human genome. While normally inactive, environmental stimuli such as infections have contributed to the transcriptional reactivation of HERV-promoting pathological conditions, including the development of autoimmunity, neurodegenerative disease and cancer. What infections trigger HERV activation? subspecies (MAP) is a pluripotent driver of human disease.
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