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Pharmacologic Management of Heart Failure with Preserved Ejection Fraction (HFpEF) in Older Adults.
Drugs Aging
January 2025
Program for the Care and Study of the Aging Heart, Department of Medicine, Weill Cornell Medicine, 420 East 70th St, New York, NY, LH-36510063, USA.
There are several pharmacologic agents that have been touted as guideline-directed medical therapy for heart failure with preserved ejection fraction (HFpEF). However, it is important to recognize that older adults with HFpEF also contend with an increased risk for adverse effects from medications due to age-related changes in pharmacokinetics and pharmacodynamics of medications, as well as the concurrence of geriatric conditions such as polypharmacy and frailty. With this review, we discuss the underlying evidence for the benefits of various treatments in HFpEF and incorporate key considerations for older adults, a subpopulation that may be at higher risk for adverse drug events.
View Article and Find Full Text PDFMoral distress, attitude toward death, and palliative care core competencies among ICU nurses: a cross-sectional study.
BMC Palliat Care
January 2025
Department of Nursing, First Affiliated Hospital of Dali University, No.32, Carlsberg Avenue, Dali City, 671007, Yunnan Province, China.
Background: Palliative care is becoming more widely acknowledged as a crucial part of intensive care for all patients with life-threatening illnesses. Intensive care unit (ICU) nurses regard as a lead role to facilitate this integration, which require nurses to possess professional and comprehensive core competencies. However, there is little knowledge about the palliative care core competencies among ICU nurses.
View Article and Find Full Text PDFA Framework for Behavioral Health Integration in the Program of All-Inclusive Care for the Elderly (PACE).
J Am Geriatr Soc
January 2025
New York State Psychiatric Institute, New York, New York, USA.
Background: The Program of All-inclusive Care for the Elderly (PACE) is a comprehensive care model that aims to promote aging in the home and community for older adults who are nursing-home eligible needs-wise. Older adults experience age-related barriers to accessing behavioral health (BH) services. PACE programs play an important role in providing all-inclusive health care for individuals over 55 who are dually eligible for Medicaid and Medicare.
View Article and Find Full Text PDFTrisomy 18 and the possibility of choice: The importance of Perinatal Hospice's support.
Eur J Pediatr
January 2025
Unit of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, Rome, Italy.
Trisomy 18 is a severe aneuploidy associated with multiple malformations and a poor prognosis. The diagnosis is typically made prenatally, leading to a high rate of pregnancy terminations. The aim of this study is to demonstrate that even though the prognosis is heterogeneous, prolonged survival is possible and these children are an enrichment for their families after all.
View Article and Find Full Text PDFAnalysis of radiation oncology integration within general practitioners' daily patient care: a cross-sectional survey in Germany.
Strahlenther Onkol
January 2025
Department of Radiation Oncology, Klinikum rechts der Isar, School of Medicine and Health, Technical, University of Munich (TUM), Ismaninger Str. 22, 81675, Munich, Germany.
Purpose: General practitioners (GPs) play a crucial role in providing interdisciplinary care for radiation oncology patients. This study aims to understand the specific needs and challenges faced by general practitioners in Germany when treating oncology patients.
Methods: A comprehensive web-based questionnaire with 24 items was disseminated to GPs in Germany via email using survio.
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