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Article Abstract
This Letter describes the synthesis and SAR of the novel positive allosteric modulator, VU0155041, a compound that has shown in vivo efficacy in rodent models of Parkinson's disease. The synthesis takes advantage of an iterative parallel synthesis approach to rapidly synthesize and evaluate a number of analogs of VU0155041.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752865 | PMC |
| http://dx.doi.org/10.1016/j.bmcl.2009.07.072 | DOI Listing |
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