Demineralized bone matrix and cancellous bone chips in a reverse-phase medium carrier (DynaBlast, Keystone Dental) were used to augment the maxillary sinuses in 8 patients requiring 10 sinus augmentations. Clinical reentry after 6 to 7 months (mean, 6.2 months) and computed tomographic scan evaluation at 5 months demonstrated new bone formation as well as sufficient radiopaque volume to place implants in all sites. Microcomputed tomographic evaluation and histomorphometric analysis of sinus core biopsies confirmed the formation of new bone and demonstrated three distinctive mineralization patterns that have been previously described. DynaBlast can be considered a viable alternative to the use of autogenous bone or other types of grafting materials.
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J Orthop
February 2025
Department of Orthopaedics, University of KwaZulu Natal, South Africa.
Background: Osteogenic Bone Matrix (Altis™ OBM) is a tissue-engineered, porcine-derived demineralized bone matrix prepared using a humanization processing technology that confers biocompatibility and improved osteoinductivity. The objective of this study was to determine the safety and efficacy of OBM in patients with traumatic long bone defects in an open-label, non-randomized single-center study.
Methods: Diagnosis and main criteria for inclusion were open long bone fractures graded as Gustilo-Anderson Grade II, IIIA or IIIB.
J Oral Maxillofac Pathol
October 2024
Department of Oral Pathology and Microbiology, Bareilly International University, Institute of Dental Sciences, Bareilly, UP, India.
Context: Platelet concentrates are rich in growth factors that assist in regenerative medicine to promote healing and tissue regeneration. Similarly, partially demineralized tooth is a storehouse of many growth factors, assisting in bone regeneration. Hence, the present study aimed to quantify the release of growth factors from different platelet concentrates individually and when mixed with a partially demineralized tooth matrix.
View Article and Find Full Text PDFOral Maxillofac Surg
December 2024
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Prince of Songkla University, Hat Yai, 90112, Songkhla, Thailand.
Am J Emerg Med
November 2024
Department of Emergency Medicine, University of Ottawa, Ottawa, Canada. Electronic address:
Introduction: Multiple myeloma (MM) and its complications carry a high rate of morbidity and mortality.
Objective: This review evaluates MM and its complications, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.
Discussion: MM is the second most common hematologic cancer and associated with monoclonal plasma cell proliferation.
J Imaging Inform Med
December 2024
Department of Radiology, USF Health, Tampa, USA.
Small cohorts of certain disease states are common especially in medical imaging. Despite the growing culture of data sharing, information safety often precludes open sharing of these datasets for creating generalizable machine learning models. To overcome this barrier and maintain proper health information protection, foundational models are rapidly evolving to provide deep learning solutions that have been pretrained on the native feature spaces of the data.
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