Porokeratosis represents a heterogeneous group of disorders characterized clinically by a distinctive ridge-like border and histologically by cornoid lamellae. A verrucous variant of porokeratosis involving the gluteal cleft has been recently described. We present 5 new cases and review the current literature to highlight the clinical and histopathologic features of this disorder. Descriptive terms including hyperkeratotic porokeratosis, genitogluteal porokeratosis, porokeratoma, follicular porokeratosis, and porokeratosis ptychotropica have all been used to describe this verrucous variant of porokeratosis involving the gluteal cleft. To avoid further confusion, we propose a consolidation of terminologies and suggest verrucous porokeratosis be added to the commonly described variants of porokeratosis.
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http://dx.doi.org/10.1111/j.1600-0560.2009.01387.x | DOI Listing |
Dermatol Online J
August 2024
University of Michigan Medical School, Ann Arbor, Michigan, USA.
We present a 44-year-old man with metastatic clear cell renal cell cancer undergoing treatment with nivolumab immunotherapy. Three months post-initiation, he developed symmetric recurrent nodules and boils in intertriginous areas, diagnosed as stage II hidradenitis suppurativa of the groin and gluteal cleft. The progressive course, lesion symmetry and location, worsening with nivolumab infusions, and biopsy findings supported the diagnosis.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
Department of Surgery, Stanford University School of Medicine, United States of America. Electronic address:
Introduction And Importance: Pilonidal disease may present with a draining secondary sinus or granuloma, but the development of these findings is not well-characterized.
Case Presentation: Two adolescent males presented with pilonidal disease. The first patient had a gluteal cleft abscess, and an incision and drainage procedure was performed.
Acta Derm Venereol
October 2024
Department of Dermatology, National University Hospital, Singapore; Department of Medicine, National University of Singapore, Singapore.
Porokeratosis ptychotropica (PP) is a rare and unusual variant of porokeratosis. There is a dearth of information on the natural history, epidemiology, and optimal treatment options. This study aimed to characterize the worldwide distribution, epidemiology, clinical features, and treatments attempted for all reported cases of porokeratosis ptychotropica.
View Article and Find Full Text PDFCureus
September 2024
Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, IND.
Ann Surg Open
September 2024
Department of Surgery, Nemours Surgical Outcomes Center, Nemours Children's Health, Delaware Valley, Wilmington, DE.
Objective: To investigate the heterogeneity of treatment effects (HTE) of laser epilation in preventing pilonidal disease recurrence through analysis of prespecified clinical factors.
Background: Pilonidal disease is a common, painful disease affecting 1% of the population aged 15 to 30 years with postoperative recurrence rates as high as 30% to 40%.
Methods: Single-institution randomized controlled trial from September 2017 to September 2022 with 1-year follow-up, including patients aged 11 to 21 years with pilonidal disease undergoing gluteal cleft laser epilation and standard care (improved hygiene and mechanical or chemical depilation) or standard care alone.
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