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| http://dx.doi.org/10.3238/arztebl.2008.0162a | DOI Listing |
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Dynamic Hydrogel-Based Strategy for Traumatic Brain Injury Modeling and Therapy.
CNS Neurosci Ther
January 2025
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Traumatic brain injury (TBI) is one of the most traumatizing and poses serious health risks to people's bodies due to its unique pathophysiological characteristics. The investigations on the pathological mechanism and valid interventions of TBI have attracted widespread attention worldwide. With bio-mimic mechanic cues, the dynamic hydrogels with dynamic stiffness changes or reversible crosslinking have been suggested to construct the in vitro disease models or novel therapeutic agents for TBI.
View Article and Find Full Text PDFNonmass Lesions on Breast Ultrasound: Interreader Agreement and Associations With Malignancy.
AJR Am J Roentgenol
December 2024
Department of Radiology, Research Institute of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Republic of Korea.
Nonmass lesions (NMLs) on breast ultrasound lack clear definition and encompass a broad range of benign and malignant entities. Given anticipated inclusion of NMLs in the BI-RADS 6th edition, thorough understanding of these lesions will be critical for optimal management. To evaluate interreader agreement for classification of lesions on breast ultrasound as NMLs and to identify imaging features associated with malignancy in these lesions.
View Article and Find Full Text PDFA Need for Clarification Regarding Current State-of-the-Art Techniques for Characterizing Lung Parenchymal Aeration?
Radiol Cardiothorac Imaging
December 2024
Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Str 1, OE 8220, 30625 Hannover, Germany.
Relation Between Chest Radiography Results and Antibiotic Initiation in Community-Acquired Pneumonia Management by General Practitioners.
Ann Fam Med
November 2024
Université Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.
Purpose: For most guidelines, diagnosis of community-acquired pneumonia (CAP) is based on a combination of clinical signs and focal consolidation visible on chest radiographs (CRs). Our objective was to analyze antibiotic initiation by general practitioners for patients with suspected CAP according to CR.
Methods: We conducted a prospective cross-sectional study in general practice in France.
Is there a relationship between CSF Interleukin 34 Level and clinicoradiological activity and IgG index in patients with MS?
Mult Scler Relat Disord
December 2024
Sivas Cumhuriyet University, Faculty of Medicine, Department of Neurology, Sivas, Turkey.
Article Synopsis
- Multiple sclerosis (MS) is an autoimmune disease whose mechanisms are being studied to improve prognosis and treatment options, focusing on Interleukin 34 (IL-34) for its potential role in MS activity.
- A study with 52 MS patients assessed CSF IL-34 levels over a year, comparing those with clinical/radiological activity to those without, and to a control group.
- Findings showed higher IL-34 levels in MS patients than controls, but no significant correlation with disease activity, suggesting IL-34 may be an important biomarker for MS pathogenesis despite not being linked to clinical symptoms.
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