Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jaci.2009.05.023 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Phototherapy as an alternative in the treatment of chronic spontaneous urticaria.
Front Allergy
November 2024
Allergy Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Chronic spontaneous urticaria (CSU) is defined as the occurrence of hives, angioedema, or both, lasting for more than 6 weeks. The treatment is based on the use of antihistamines, omalizumab, and/or cyclosporine following a stepwise algorithm recommended by international guidelines with a high level of evidence. Nevertheless, management can be challenging as some patients do not respond to the suggested drugs or have difficulties accessing them for various reasons.
View Article and Find Full Text PDFThe use and implementation of omalizumab as food allergy treatment: Consensus-based guidance and Work Group Report of the Adverse Reactions to Foods Committee of the American Academy of Allergy, Asthma & Immunology.
J Allergy Clin Immunol
November 2024
Section of Allergy and Clinical Immunology, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colo. Electronic address:
Omalizumab was recently approved by the US Food and Drug Administration for treatment of any single food allergy or multiple food allergies in children aged 1 year and older and adults. There is currently no formal guidance regarding recommended best practices for omalizumab use in food allergy, including patient selection, anticipated goals and outcomes of therapy, procedure for monitoring patients who elect to start omalizumab therapy, and ways in which omalizumab can be incorporated into the landscape of food allergy management and daily clinical practice. This work group report was developed by the food allergy therapies subcommittee of the Adverse Reactions to Foods Committee within the American Academy of Allergy, Asthma & Immunology.
View Article and Find Full Text PDFAnti-IgE therapy in chronic rhinosinusitis with nasal polyps.
J Allergy Clin Immunol
November 2024
Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States. Electronic address:
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition characterized by type 2 (T2) immune responses with significant impacts on quality of life and healthcare costs. Local IgE production in nasal polyp tissue plays a key role in the T2 inflammatory cascade. Omalizumab, an anti-IgE monoclonal antibody, is an effective treatment for some patients with CRSwNP regardless of the patient's allergic status.
View Article and Find Full Text PDFBiological Effects and Clinical Application of the Anti-Immunoglobulin E Antibody.
Int Arch Allergy Immunol
November 2024
Department of Dermatology and Venereology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Background: Immunoglobulin E (IgE) plays a pivotal role in the pathogenesis of allergic diseases by engaging with FcεRI and FcεRII receptors, triggering allergic responses. The development of anti-IgE antibodies, such as omalizumab, has introduced a targeted approach to allergy treatment by neutralizing free IgE and dampening the allergic cascade.
Summary: This review synthesizes the current understanding of IgE's role in allergic diseases and evaluates the clinical utility of omalizumab.
Aquagenic urticaria: presentation, diagnosis and management.
BMJ Case Rep
November 2024
Memorial University of Newfoundland Faculty of Medicine, St. John's, Canada.
Aquagenic urticaria, a rare dermatological condition characterised by urticarial eruptions following water contact, poses significant diagnostic and therapeutic challenges. This condition, although uncommon, necessitates heightened clinical awareness due to its substantial impact on the patient's quality of life. We present a comprehensive account of a paediatric case involving a girl in her mid-teens, who developed recurrent wheals post-exposure to water, independent of its temperature or source.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!