Since 2002, an MS Registry has been implemented by the German MS Society in more than 100 German MS centres. The objective is to provide information about disease characteristics, and to monitor the health care situation in a large population of patients. The aim of this report is to give detailed results on MS symptoms. By October 2008, data sets from 16,554 patients were recorded by 86 centres. A strikingly high number of persons suffered from fatigue and other "invisible" symptoms during early and late stages of the disease, underscoring the negative impact of these symptoms on quality of life in MS patients.
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| http://dx.doi.org/10.1007/s00415-009-5257-5 | DOI Listing |
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Nervenarzt
December 2024
Klinik für Psychiatrie und Psychotherapie, CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Deutschland.
Background: At present there is no comprehensive overview of the long-term development of the clinical picture, disease-associated impairments and neurobiological correlates of anxiety disorders as well as what influence certain risk factors and treatment have on the prognosis.
Objective: This article presents findings regarding disorder-specific symptoms and disorder-associated changes in the areas of functional level, quality of life, neurocognitive performance and structural brain anatomy over the lifespan. It also reports on how patient-related and environment-related aspects as well as guideline-oriented therapy influence the course of the disorder.
Decomposing the Brain in Autism: Linking Behavioral Domains to Neuroanatomical Variation and Genomic Underpinnings.
Biol Psychiatry Cogn Neurosci Neuroimaging
December 2024
Department of Child and Adolescent Psychiatry, University Hospital, Goethe University, 60528 Frankfurt am Main, Germany; Brain Imaging Center, Goethe-University, 60528 Frankfurt am Main, Germany; Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, SE5 8AF, UK.
Background: Autism is accompanied by highly individualized patterns of neurodevelopmental differences in brain anatomy. This variability makes the neuroanatomy of autism inherently difficult to describe at the group level. Here, we examined inter-individual neuroanatomical differences using a dimensional approach that decomposed the domains of social communication and interaction (SCI), restricted and repetitive behaviors (RRB), and atypical sensory processing (ASP) within a neurodiverse study population.
View Article and Find Full Text PDFLocalizing value of disturbances of self-integration, depersonalization, and forced thinking: A systematic review.
Epileptic Disord
December 2024
National Center for Epilepsy, Member of the ERN EpiCARE, Oslo University Hospital, Oslo, Norway.
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View Article and Find Full Text PDFAcceptability, User Satisfaction, and Feasibility of an App-Based Support Service During the COVID-19 Pandemic in a Psychiatric Outpatient Setting: Prospective Longitudinal Observational Study.
JMIR Form Res
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Department of Psychiatry and Psychotherapy, Medical Faculty, Leipzig University, Leipzig, Germany.
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Salivary testosterone is associated with feelings of senselessness and self-dislike in women with borderline personality disorder.
Eur J Psychotraumatol
December 2024
Department of Psychiatry and Psychotherapy, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt- Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Article Synopsis
- Women with borderline personality disorder (BPD) have higher baseline testosterone levels, prompting researchers to explore the relationship between salivary testosterone and specific BPD symptoms.
- The study involved 98 women with BPD, assessing their testosterone levels and emotional symptoms using self-rating scales for BPD severity and depression.
- Results indicated that higher testosterone was linked to overall increased symptom severity, particularly associated with negative self-perception and depressive feelings, rather than the expected aggressive or impulsive behaviors.
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