Nosocomial infections represent a serious public health problem. Some recent studies, most of which used strong educational programs, showed a dramatic decrease in the rates of nosocomial infections, particularly catheter-related infections in the intensive care unit. Thus, the concept of "zero risk" is flourishing in the recent literature, and some insurance networks have decided to limit reimbursement for treatment of some of the health care-associated infections, on the grounds that most of them are preventable. This viewpoint article emphasizes the risk of such a position and enumerates the reasons why such a philosophy could be counterproductive. In particular, this philosophy does not fit with the concept of self-declaration of severe adverse events and could push clinicians to underreport those events.
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http://dx.doi.org/10.1086/604720 | DOI Listing |
Mem Inst Oswaldo Cruz
December 2024
Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Pesquisa em Malária / Centro de Pesquisa, Diagnóstico e Treinamento em Malária, Laboratório de Referência do Ministério da Saúde para Diagnóstico de Malária na Região Extra-Amazônica, Rio de Janeiro, RJ, Brasil.
Background: Although blood transfusion is an essential therapeutic procedure, it can present risks, including transmitting infectious diseases, such as malaria. In Acre, the thick blood smear microscopic examination (TBS) is used to screen infected malaria blood donors. However, TBS has low sensitivity for detecting Plasmodium in situations of low parasitaemia, such as those presented by asymptomatic clinically healthy individuals.
View Article and Find Full Text PDFJBJS Essent Surg Tech
December 2024
Sports Medicine Center, Department of Orthopaedics, Massachusetts General Hospital, Mass General Brigham, Boston, Massachusetts.
Background: Whereas uncomplicated labral tears with preserved fibers can be effectively treated with use of labral repair techniques, complex tears and hypoplastic labra require labral reconstruction. Standard reconstruction techniques feature grafted tissue that is added to existing, deficient tissue or that is utilized to replace a hypoplastic labrum entirely. However, such approaches utilizing allografts or remote autografts are limited because they often necessitate extensive debridement of the existing labrum to prepare a site for graft implantation, an approach that can damage and devascularize the chondrolabral junction.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
November 2024
Université Paris-Saclay, INRAE, AgroParisTech, UMR ECOSYS, 91120, Palaiseau, France.
The intensification of agriculture has promoted the simplification and specialization of agroecosystems, resulting in negative impacts such as decreasing landscape heterogeneity and increasing use of plant protection products (PPP), with the acceleration of PPP transfers to environmental compartments and loss in biodiversity. In this context, the present work reviews the various levers for action promoting the prevention and management of these transfers in the environment and the available modelling tools. Two main categories of levers were identified: (1) better control of the application, including the reduction of doses and of PPP dispersion during application thanks to appropriate equipment and settings, PPP formulations and consideration of meteorological conditions; (2) reduction of post-application transfers at plot scales (soil cover, low tillage, organic matter management, remediation etc.
View Article and Find Full Text PDFJ Viral Hepat
December 2024
Barts Liver Centre, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Lancet HIV
November 2024
Prevention Access Campaign, New York, NY, USA.
To end AIDS as a public health threat by 2030, we must leverage both the impactful message of U=U (undetectable equals untransmittable) and viral suppression to improve the wellbeing of individuals living with HIV, increase engagement with HIV services, and reduce barriers such as stigma, discrimination, and criminalisation. This message requires clear and unambiguous evidence-based narratives that emphasise the message that there is zero risk of sexual transmission when an undetectable viral load is maintained and negligible risk when viral suppression (as defined by 200-1000 copies per mL) is maintained. Dissemination of this information to individuals living with or affected by HIV, health-care workers, communities, the general public, and policy makers will increase awareness and credibility of this message and challenge deep-seated misperceptions.
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