Aim: To study prevalence of hemolytic Escherichia in microbiocenosis of large intestine in 501 adult persons from Rostov-on-Don city.
Materials And Methods: Comparison of qualitative and quantitative composition of large intestine microbiocenosis in 248 persons with ultrasound examination of functional state of biliary tract was performed.
Results: Statistically significant dependence of the rate of hemolytic Escherichia detection in microflora of large intestine from presence of dysfunctional disorders of biliary tract (biliary tract dysfunction) was revealed. Difference in character of microecological changes in large intestine of patients with such disorders and persons treated with wide-spectrum antibiotics was established. It was revealed that main feature of large intestine dysbiosis in patients with biliary tract dysfunction was the presence of significant quantity of hemolytic Escherichia as part of this compartment's microflora.
Conclusion: Hypothesis about possible role of functional disorders of biliary tract as a primary cause of microecologic imbalance was proposed.
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Gut Microbes
December 2025
Microbiome-Host Interactions, Institut Pasteur, Université Paris Cité, INSERM U1306, CNRS UMR6047, Paris, France.
Metabolic syndrome is, in humans, associated with alterations in the composition and localization of the intestinal microbiota, including encroachment of bacteria within the colon's inner mucus layer. Possible promoters of these events include dietary emulsifiers, such as carboxymethylcellulose (CMC) and polysorbate-80 (P80), which, in mice, result in altered microbiota composition, encroachment, low-grade inflammation and metabolic syndrome. While assessments of gut microbiota composition have largely focused on fecal/luminal samples, we hypothesize an outsized role for changes in mucus microbiota in driving low-grade inflammation and its consequences.
View Article and Find Full Text PDFMicrob Pathog
January 2025
Jiangsu Agri-Animal Husbandry Vocational College, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou 225300, PR China. Electronic address:
Goose astrovirus (GAstV) poses a large threat to the goose industry in China, with two genotypes: goose astrovirus genotype 1 (GAstV-1) and GAstV-2. GAstV-2 causes gout in goslings; however, understanding of GAstV-1 is limited. In this study, the GAstV-1 strain JY202323, was isolated from dead goslings, and its complete genome sequence was obtained using next-generation sequencing.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
There are limited studies on the improvement of leaky gut with minor inflammation associated with various diseases. To explore the therapeutic potential of Lactiplantibacillus plantarum 22 A-3, a member of the Lactobacillus species, in addressing a leaky gut. Lactiplantibacillus plantarum 22 A-3 was administered to a leaky gut mice model with low dextran sulfate sodium concentrations.
View Article and Find Full Text PDFZhonghua Fu Chan Ke Za Zhi
January 2025
Zhonghua Bing Li Xue Za Zhi
February 2025
Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, U S A.
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