AI Article Synopsis
- The study examines the prevalence of dementia and Alzheimer's Disease (AD) in Kerala, South India, revealing significant rates among the aging population.
- Findings show that 3.77% of individuals aged 55 and older and 4.86% of those aged 65 and older were diagnosed with dementia, with higher rates observed in older and less-educated individuals.
- The research concludes that dementia and AD are more common in Kerala than previously recognized, with increased age and low education being risk factors for dementia, while female gender is associated with a higher prevalence of AD.
Article Abstract
Background: Data on the prevalence of dementia in India with a large and aging population is scant. We studied prevalence of AD and dementia in Kerala, South India, and effects of age, education and gender on it.
Methods: 2-phase survey on 2466 individuals aged > or = 55 years living in community. Men constituted 41%, < 75 years age in 76.9% and education > or = 4 years in 69.6%. Screening (Phase I) using the instrumental activity of daily living scale for the elderly (IADL-E) and the Addenbrooke's cognition examination (ACE). Diagnostic-assessment (Phase II) was in 532 screen-positives and 247 (10%) screen-negatives.
Results: 93 (3.77%) > or = 55 years and 81 (4.86%) > or = 65 years of age had dementia. Age adjusted (against US-population in 2000) dementia (and AD) rates were 4.86% (1.91%) in age > or = 55 years and 6.44% (3.56%) in > or = 65 years. Odds for dementia (and AD) were high with increasing-age 5.89 (15.33) in 75-84, 13.23 (25.92) > or = 85 years, and in women 1.62 (2.95); and low 0.27 (0.16) if education was > or = 9 years. Age and low education increased dementia. Age and female gender increased AD.
Conclusion: Prevalence of dementia and AD is higher than any reported from the subcontinent suggesting that dementia in Kerala in South India is not uncommon. Increasing age increased dementia and AD. Low-education is associated with dementia and female-gender with AD.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367932 | PMC |
| http://dx.doi.org/10.1002/gps.2338 | DOI Listing |
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