Systemic lymphoma that involves the aorta is called periaortic lymphoma, and may be misdiagnosed clinically or in CT sean, mimicking a thoracic aortic aneurysm, dissection, penetrating ulcer or an intramural hematoma. We report a 70 year-old woman in whom a systemic non-Hodgkin 's lymphoma ivas diagnosed after she presented with the clinical features of an acute aortic syndrome. A CT sean showed the presence of a large thoracoabdominal periaortic soft tissue mass without aneurism or dissection. Later, a biopsy of the mass ivasperformed which showed a non-Hodgkin's lymphoma. Chemotherapy with CHOP-R was effective, with complete initial resolution of the mass, developing in the follow up chylothorax, malnutrition and death.
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Int J Surg Case Rep
December 2024
Santa Casa de Misericordia de Santos, Divisão de Urologia, Departamento de Cirurgia, Santos, São Paulo, Brazil; Faculdade de Medicina, Universidade Metropolitana de Santos (UNIMES), Departamento de Urologia, Santos, São Paulo, Brazil.
Introduction And Importance: Retroperitoneal fibrosis is a proliferative disease of fibroblasts with a still unclear appearance and low incidence. The clinical manifestations are nonspecific and appear late, pain is the most common symptom present. Elevated serum IgG4 levels are observed in up to 60 % of the patients and the main goal of treating this condition is to preserve kidney function.
View Article and Find Full Text PDFCureus
March 2024
Internal Medicine, Ospedale San Pietro Fatebenefratelli, Roma, ITA.
Retroperitoneal fibrosis (RPF) is a rare condition characterized by the presence of fibro-inflammatory tissue surrounding the abdominal aorta and iliac arteries, often leading to the involvement of adjacent organs such as the ureters and inferior vena cava. We present a case report of a 56-year-old Caucasian woman with a complex medical history, including Hodgkin's lymphoma treated with chemotherapy and radiotherapy (31 years before), a significant smoking history, and a current presentation of acute kidney injury with oliguria, edema, and hypertension. Initial diagnostic considerations included rapidly progressive glomerulonephritis, supported by clinical and imaging findings.
View Article and Find Full Text PDFMod Rheumatol Case Rep
July 2024
Department of Clinical Immunology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Lymphoproliferative disorders (LPDs) are serious complications that arise in patients with rheumatoid arthritis (RA) receiving immunosuppressive drugs (ISDs). Here, we reported a 73-year-old woman diagnosed with RA at 60 years of age and treated with methotrexate, bucillamine, prednisolone, and infliximab. She was referred to our hospital, Osaka Metropolitan University Hospital, with general malaise, pancytopenia, a right adrenal mass, and enlarged periaortic lymph nodes.
View Article and Find Full Text PDFIndian J Urol
March 2023
Department of Urology, AIIMS, Jodhpur, Rajasthan, India.
A 67-year-old male was incidentally found to have a large left perinephric mass with a poorly functioning left kidney. A differential diagnosis of renal cell carcinoma, lymphoma, retroperitoneal fibrosis (RPF), and IgG4 renal disease was suggested on imaging studies and biopsy of the mass. A left radical nephrectomy was performed as malignancy could not be ruled out.
View Article and Find Full Text PDFJACC Case Rep
June 2023
Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Diffuse large B-cell lymphoma (DLBCL) is an aggressive lymphoma that is fatal if left untreated. Few cases have been reported of involvement of the aorta. Here we present a case of DLBCL that was diagnosed by periaortic computed tomography-guided biopsy.
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