A novel lipid-transporting protein (Ns-LTP1) has been isolated from seeds of the garden fennel flower Nigella sativa. The molecular mass, N-terminal amino acid sequence, and amino acid composition of the protein have been determined. Ns-LTP1 has a molecular mass of 9602 Da and contains eight cysteine residues which form four disulfide bridges. The protein is capable of suppressing the development of some phytopathogenic fungi and oomycetes.
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The Vps13-like protein BLTP2 is pro-survival and regulates phosphatidylethanolamine levels in the plasma membrane to maintain its fluidity and function.
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Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Article Synopsis
- Lipid transport proteins (LTPs) are essential for moving lipids between different parts of the cell and maintaining lipid balance, with a new family of proteins called bridge-like LTPs (BLTPs) forming connections for lipid transport between organelles.* -
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M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, 117997 Moscow, Russia.
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