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Controlled lipid digestion in the development of functional and personalized foods for a tailored delivery of dietary fats.
Food Chem
February 2025
Department of Animal Product Technology, Faculty of Food Technology, University of Agriculture, Balicka 122, 30-149 Kraków, Poland.
In recent decades, obesity and its associated health issues have risen dramatically. The COVID-19 pandemic has further exacerbated this trend, underscoring the pressing need for new strategies to manage weight. Functional foods designed to modulate lipid digestion and absorption rates and thereby reduce the assimilation of dietary fats have gained increasing attention in food science as a potentially safer alternative to weight-loss medications.
View Article and Find Full Text PDFCo-administration of Ayurvedic medicines Arshogrit and Jatyadi Ghrit, attenuate croton oil-induced hemorrhoids in rat model of recto-anal inflammation by modulating TNF-α and IL-1β levels.
Drug Dev Ind Pharm
November 2024
Drug Discovery and Development Division, Patanjali Research Foundation, Haridwar, India.
Objective: To study the efficacy of co-administration of Arshogrit (AG) and Jatyadi Ghrit (JG), two herb-based Ayurvedic medicines, in rat model of croton oil-induced hemorrhoids.
Significance: Hemorrhoids refer to a pathological condition affecting the recto-anal region causing pain, swelling, bleeding and protrusion. The available therapies for hemorrhoids are symptomatic or invasive but are expensive and associated with adverse effects.
Red Wine Consumption and the Impact on Cardiovascular Health: The Methodological Barriers of Observational Study Design.
J Med Food
November 2024
Department of Dietetics and Nutritional Science, School of Health Sciences and Education, Harokopio University, Athens, Greece.
Cardiovascular disease (CVD) is the leading cause of death among communicable and noncommunicable diseases, and its prevalence is going to rise even more by 2030. The discovery of different "functional" foods containing a plethora of bioactive compounds is considered an ally in the effort to reduce the global CVD burden in the context of primary prevention. It has been about 3 decades since the observation that red wine consumption in French population could lead to lower coronary heart disease risk despite the high dietary consumption of saturated fats, known as the "French paradox.
View Article and Find Full Text PDFInvestigating the effects of co-supplementation with alpha-linolenic acid and L-carnitine on inflammatory status, oxidative stress, clinical symptoms, mental health and quality of life in women with migraine: a protocol for a randomized, triple-blind, placebo-controlled trial.
Trials
October 2024
Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Article Synopsis
- Migraine is a common and debilitating neurological disorder, with potential contributing factors including inflammation, oxidative stress, and nutrient deficiencies; nutrition-based approaches might provide safer and more affordable symptom management.
- This study will randomly assign 80 women aged 20 to 50 to receive a co-supplement of alpha-linolenic acid and L-carnitine, or placebos, over 12 weeks, aiming to measure the effectiveness through migraine symptoms and various health markers.
- The research aims to explore whether the combination of these nutrients can improve migraine symptoms, as well as impact mental health, sleep quality, and overall quality of life for patients.
Cytokine Release Syndrome Associated With Immune-Modulating Chemotherapy: Potential Mitigating Role of Intravenous Omega-3 Fatty Acid Triglycerides.
Cancer Rep (Hoboken)
October 2024
Harvard Medical School, Boston, Massachusetts, USA.
Background: Patient susceptibility to cytokine release syndrome (CRS) resulting from immune-modulating chemotherapy has profound implications for clinical outcome. This is particularly true for patients receiving CAR T-cell therapy. First-line pharmacotherapy for CRS includes the administration of the IL-6 receptor-binding monoclonal antibody tocilizumab, or tocilizumab and corticosteroids.
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