AI Article Synopsis
- The esat-6 and cfp-10 genes play a crucial role in the virulence of Mycobacterium tuberculosis.
- Among non-tuberculous mycobacteria, these genes were only identified in four species: M. kansasii, M. szulgai, M. marinum, and M. riyadhense, each having unique sequences.
- This discovery contributes to understanding the evolutionary relationships and classification of these bacteria and may suggest a potential virulence factor in non-tuberculous mycobacteria.
Article Abstract
The esat-6 and cfp-10 genes are essential for virulence in Mycobacterium tuberculosis. Among nontuberculous mycobacteria, we found these genes only in M. kansasii, M. szulgai, M. marinum, and M. riyadhense, with unique sequences. This adds a phylogenetic and taxonomical characteristic and may represent a virulence factor for nontuberculous mycobacteria.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737943 | PMC |
| http://dx.doi.org/10.1128/JB.00683-09 | DOI Listing |
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